Increase of creatine kinase activity in the visual cortex of human brain during visual stimulation: A 31p NMR magnetization transfer study

Increase of creatine kinase activity in the visual cortex of human brain during visual stimulation: A 31p NMR magnetization transfer study
复制标题

视觉刺激期间人脑视觉皮层肌酸激酶活性的增加:31p NMR 磁化转移研究

DOI:
--
复制
发表时间:
1997
影响因子:
3.3
通讯作者:
K. Uğurbil
K. Uğurbil
中科院分区:
医学3区
文献类型:
--
作者:
Wei Chen;Xiao;G. Adriany;K. Uğurbil

文献摘要

参考文献

被引文献

相似文献

采用31P磁共振波谱法研究光刺激下人视觉皮层高能磷酸水平和肌酸激酶(CK)动力学的变化。通过测量“正向”方向(即磷酸肌酸合成ATP的方向)的表观单向速率常数(kf)来评估CK动力学。在刺激期间,视觉皮层区域的kf增加了34%,而高能磷酸盐化合物的稳态浓度没有显著变化,这表明在神经元活动增加期间CK周转增加。
31P magnetic resonance spectroscopy was used to investigate changes in high energy phosphate levels and creatine kinase (CK) kinetics induced in the human visual cortex during photic stimulation. CK kinetics was evaluated by measuring the apparent unidirectional rate constant (kf) in the “forward” direction (i.e., in the direction of ATP synthesis from phosphocreatine). kf increased 34% in the visual cortex areas during stimulation without significant changes of steady‐state concentration of high energy phosphate compounds, indicating that CK turnover is elevated during increased neuronal activity.
DOI: 10.1073/pnas.83.4.1140
发表时间: 1986-02-01
影响因子: 11.1
作者:
FOX, PT;RAICHLE, ME
通讯作者: RAICHLE, ME
DOI: 10.1126/science.3260686
发表时间: 1988-07-22
期刊: SCIENCE
影响因子: 56.9
作者:
FOX, PT;RAICHLE, ME;DENCE, C
通讯作者: DENCE, C
DOI: 10.1073/pnas.89.12.5675
发表时间: 1992-06-15
影响因子: 11.1
作者:
KWONG, KK;BELLIVEAU, JW;ROSEN, BR
通讯作者: ROSEN, BR
DOI: 10.1126/science.3704638
发表时间: 1986-05-30
期刊: SCIENCE
影响因子: 56.9
作者:
BALABAN, RS;KANTOR, HL;BRIGGS, RW
通讯作者: BRIGGS, RW
完整心脏中肌酸激酶和 ATP 酶速率的磁化转移测量。
DOI: --
发表时间: 1985
期刊: Circulation
影响因子: 37.8
作者:
Ugurbil,K
通讯作者: Ugurbil,K