Folding of the anterior cingulate cortex partially explains inhibitory control during childhood: a longitudinal study.
Folding of the anterior cingulate cortex partially explains inhibitory control during childhood: a longitudinal study.
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DOI：
10.1016/j.dcn.2014.02.006
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发表时间：
2014-07
影响因子：
4.7
通讯作者：
Houdé O
中科院分区：
文献类型：
--
作者：
Borst G;Cachia A;Vidal J;Simon G;Fischer C;Pineau A;Poirel N;Mangin JF;Houdé O
认知控制的困难与几种精神疾病有关。儿童的抑制控制（IC）预测学术和专业的成功。5岁时的ACC沟模式与5岁时的IC效率（Stroop评分）相关。5岁时的ACC沟模式解释了9岁时的IC效率（Stroop评分）。ACC脑沟模式限制儿童期IC效率。包括抑制控制（IC）在内的认知控制困难与几种精神疾病的病理生理学有关。在健康的受试者中，儿童时期的IC效率是日后学业和职业成功的有力预测因素。背侧前扣带皮层（ACC）是负责IC的核心结构之一。虽然ACC的定量结构特征有助于IC效率，但有助于IC发展的定性结构脑特征却不太清楚。使用解剖磁共振成像，我们调查是否ACC沟模式在5岁，一个稳定的定性特征的大脑在子宫内确定，解释IC在9岁。18名儿童在5岁和9岁时进行Stroop任务。不对称ACC沟型的儿童（n = 7）在5岁和9岁时的IC效率高于对称ACC沟型的儿童（n = 11）。ACC脑沟模式似乎影响特定的IC效率，因为ACC脑沟模式对言语工作记忆没有影响。我们的研究提供了第一个证据，证明ACC沟模式-一种出生后不受成熟和学习影响的大脑定性结构特征-部分解释了儿童时期的IC效率。
Difficulties in cognitive control are related to several psychiatric conditions. Inhibitory control (IC) of children predicts academic and professional successes. ACC sulcal patterns at age 5 were related to IC efficiency at age 5 (Stroop scores). ACC sulcal patterns at age 5 explained IC efficiency at age 9 (Stroop scores). ACC sulcal patterns constrain IC efficiency during childhood. Difficulties in cognitive control including inhibitory control (IC) are related to the pathophysiology of several psychiatric conditions. In healthy subjects, IC efficiency in childhood is a strong predictor of academic and professional successes later in life. The dorsal anterior cingulate cortex (ACC) is one of the core structures responsible for IC. Although quantitative structural characteristics of the ACC contribute to IC efficiency, the qualitative structural brain characteristics contributing to IC development are less-understood. Using anatomical magnetic resonance imaging, we investigated whether the ACC sulcal pattern at age 5, a stable qualitative characteristic of the brain determined in utero, explains IC at age 9. 18 children performed Stroop tasks at age 5 and age 9. Children with asymmetrical ACC sulcal patterns (n = 7) had better IC efficiency at age 5 and age 9 than children with symmetrical ACC sulcal patterns (n = 11). The ACC sulcal patterns appear to affect specifically IC efficiency given that the ACC sulcal patterns had no effect on verbal working memory. Our study provides the first evidence that the ACC sulcal pattern – a qualitative structural characteristic of the brain not affected by maturation and learning after birth – partially explains IC efficiency during childhood.
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影响因子：
5.7
作者：
Fischl, B;Sereno, MI;Dale, AM
通讯作者：
Dale, AM
DOI：
10.1017/s1355617701733048
发表时间：
2001-03-01
影响因子：
2.6
作者：
Brown, WS;Thrasher, ED;Paul, LK
通讯作者：
Paul, LK
影响因子：
3.7
作者：
Fornito, A;Yücel, M;Pantelis, C
通讯作者：
Pantelis, C
影响因子：
3.2
作者：
Cachia, Arnaud;Borst, Gregoire;Houde, Olivier
通讯作者：
Houde, Olivier
影响因子：
64.8
作者：
Insel, Thomas R.
通讯作者：
Insel, Thomas R.