Computational Analysis of Cardiac Contractile Function.
Computational Analysis of Cardiac Contractile Function.
复制标题
心脏收缩功能的计算分析。
DOI：
10.1007/s11886-022-01814-1
复制
发表时间：
2022-12
影响因子：
3.7
通讯作者：
Ding, Yichen
中科院分区：
文献类型：
--
作者：
Zhang, Xinyuan;Alexander, Ritzia Vinu;Yuan, Jie;Ding, Yichen
心力衰竭是世界范围内发病率和死亡率较高的疾病。心肌的力学性质是心脏功能的关键决定因素，心肌收缩力的区域变化表现在梗死心室内。因此，心肌收缩功能的定量评估是关键，以确定心肌梗死的早期诊断和治疗干预。心脏功能评估的当前进展是与成像技术的发展同步的。为高级成像量身定制的方法已广泛用于心脏磁共振、超声心动图和光学显微镜。在这篇综述中，我们介绍了基础研究和临床调查中使用的每种成像模式的基本概念和代表性方法的应用。所有这些方法都被设计或开发用于量化时间依赖性2维（2D）或3D心脏力学，具有很大的潜力来解开从收缩末期到舒张末期的全局或局部心肌变形和收缩功能。评估心脏收缩功能的计算方法为心脏发育、损伤和重塑过程中的心肌力学分析提供了定量的见解。
Heart failure results in the high incidence and mortality all over the world. Mechanical properties of myocardium are critical determinants of cardiac function, with regional variations in myocardial contractility demonstrated within infarcted ventricles. Quantitative assessment of cardiac contractile function is therefore critical to identify myocardial infarction for the early diagnosis and therapeutic intervention. Current advancement of cardiac functional assessments is in pace with the development of imaging techniques. The methods tailored to advanced imaging have been widely used in cardiac magnetic resonance, echocardiography, and optical microscopy. In this review, we introduce fundamental concepts and applications of representative methods for each imaging modality used in both fundamental research and clinical investigations. All these methods have been designed or developed to quantify time-dependent 2-dimensional (2D) or 3D cardiac mechanics, holding great potential to unravel global or regional myocardial deformation and contractile function from end-systole to end-diastole. Computational methods to assess cardiac contractile function provide a quantitative insight into the analysis of myocardial mechanics during cardiac development, injury, and remodeling.
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DOI：
10.1016/j.jaccao.2021.01.011
发表时间：
2021-03
期刊：
JACC. CardioOncology
影响因子：
--
作者：
Dobson R;Ghosh AK;Ky B;Marwick T;Stout M;Harkness A;Steeds R;Robinson S;Oxborough D;Adlam D;Stanway S;Rana B;Ingram T;Ring L;Rosen S;Plummer C;Manisty C;Harbinson M;Sharma V;Pearce K;Lyon AR;Augustine DX;British Society of Echocardiography (BSE) and theBritish Society of Cardio-Oncology (BCOS)
通讯作者：
British Society of Echocardiography (BSE) and theBritish Society of Cardio-Oncology (BCOS)
影响因子：
49.6
作者：
Bui, Anh L.;Horwich, Tamara B.;Fonarow, Gregg C.
通讯作者：
Fonarow, Gregg C.
影响因子：
7.6
作者：
Florack L;van Assen H
通讯作者：
van Assen H
影响因子：
10.9
作者：
Clarysse, P;Basset, C;Magnin, IE
通讯作者：
Magnin, IE
影响因子：
19.7
作者：
AXEL, L;DOUGHERTY, L
通讯作者：
DOUGHERTY, L