Thermo- and redox-responsive dendronized polymer hydrogels
Thermo- and redox-responsive dendronized polymer hydrogels
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热响应和氧化还原响应的树枝化聚合物水凝胶
DOI：
10.1039/c7py01284e
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发表时间：
2018-02
影响因子：
4.6
通讯作者：
Zhang Afang
中科院分区：
文献类型：
--
作者：
Zhang Xiacong;Yin Yu;Yan Jiatao;Li Wen;Zhang Afang
为了将联合收割机的树枝状结构和热响应性结合在金属超分子化学领域，以含三联吡啶（Tpy）的第一代（G1）树枝状共聚物为原料，通过亚铁离子诱导的超分子相互作用制备了一种新型的智能水凝胶.这些水凝胶显示热诱导的可逆收缩-溶胀和氧化还原介导的凝胶-溶胶转变。通过旋转流变仪的流变学分析表明，通过改变金属离子与Tpy的摩尔比以及不同OEG树枝化基元与Tpy单元比例的共聚物组成，其储能模量（G′）和损耗模量（G ″）取决于交联密度。还制备了悬挂有线性OEG单元和第二代（G2）树枝状基元的共聚物，以比较结构对水凝胶形成及其性质的可能影响。凭借这些树枝化共聚物的热响应性，通过在聚合物相变温度以上交联聚集体进一步制备水凝胶，这提供了一种方便的策略来提供具有大大改善的弹性模量的水凝胶。此外，研究了模型药物从水凝胶的包封和热介导的转变，以证明来自基于OEG的树枝化聚合物基质的独特限制。该报告不仅提供了第一条通过金属离子介导的配位从树枝化共聚物制备智能水凝胶的路线，而且还证明了通过交联热诱导聚合物聚集体可以简单地制备具有增强的机械性能的温敏水凝胶。
In order to combine dendritic structures and thermoresponsiveness within the field of metallo-supramolecular chemistry, a novel type of smart hydrogel was prepared through ferrous ion-induced supramolecular interactions from oligoethylene glycol (OEG)-based, first-generation (G1) dendritic copolymers containing terpyridine (Tpy) moieties. These hydrogels show both thermally-induced reversible shrunk-swelling and redox-mediated gel–sol transitions. Rheological analyses by rotational rheometry revealed that their storage modulus (G′) and loss modulus (G′′) were dependent on crosslinking density through changing the molar ratio of metal ions and Tpy moieties, as well as the copolymer composition with different ratios of OEG dendron and Tpy units. Copolymers pendanted with linear OEG units and second-generation (G2) dendrons were also prepared to compare the possible effects of architecture on the formation of hydrogels and their properties. By virtue of the thermoresponsiveness of these dendronized copolymers, hydrogels were further prepared through crosslinking of aggregates above the polymer phase-transition temperatures, which provides a convenient strategy to afford hydrogels with much improved elastic modulus. Moreover, encapsulation and thermally-mediated transition of the model drug from the hydrogels were investigated, to demonstrate the unique confinement from the OEG-based dendronized polymer matrix. This report provides not only a first route to fabricate intelligent hydrogels from dendronized copolymers through metal ions-mediated coordination, but also proves that thermoresponsive hydrogels with enhanced mechanical properties could be simply prepared by crosslinking thermally-induced polymer aggregates.
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影响因子：
6.6
作者：
Wei‐Xing Cheng;J. Kumar;Yong Zhang;Ye Liu
通讯作者：
Wei‐Xing Cheng;J. Kumar;Yong Zhang;Ye Liu
影响因子：
5.5
作者：
Matsunaga, Takuro;Sakai, Takamasa;Shibayama, Mitsuhiro
通讯作者：
Shibayama, Mitsuhiro
影响因子：
4.6
作者：
Dong, Yixiao;Saeed, Aram Omer;Wang, Wenxin
通讯作者：
Wang, Wenxin
影响因子：
4.6
作者：
Zhishen Ge;Shiyong Liu
通讯作者：
Zhishen Ge;Shiyong Liu
影响因子：
--
作者：
A. Zhang;Bin Zhang;Eva Wächtersbach;Manfred Schmidt;A. Schlüter
通讯作者：
A. Zhang;Bin Zhang;Eva Wächtersbach;Manfred Schmidt;A. Schlüter