Detection, counting, and imaging of single nanoparticles.
Detection, counting, and imaging of single nanoparticles.
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DOI：
10.1021/ac403890n
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发表时间：
2014-01-07
影响因子：
7.4
通讯作者：
Tao, Nongjian
中科院分区：
文献类型：
--
作者：
Wang, Wei;Tao, Nongjian
因此，发表了许多优秀的评论，涵盖了用于化学分析的纳米材料的不同方面。1− 6本综述主要关注单个纳米粒子在分析化学中的应用。单个纳米颗粒的检测、计数、成像和跟踪代表了分析化学中至关重要的能力。除了揭示纳米颗粒的基本性质，否则可能会在纳米颗粒的整体分析中被洗掉，单个纳米颗粒分析的能力提供了许多独特的应用。由于篇幅所限，本综述主要包括2011年至2013年出版的作品。纳米颗粒具有特殊的物理和化学性质，已被用于许多分析检测。研究表明，纳米颗粒的物理（如光发射和吸收7）和化学（如催化反应）性质不仅取决于其化学组成，还取决于其大小和形状。例如，发现用适体修饰的10种不同的金纳米棒（AuNR）的光学响应变化了3 - 4倍。8在另一项研究中，发现与各向同性纳米颗粒相比，高度各向异性的纳米颗粒对Hg 2+的结合更敏感。9通过分析100多个纳米颗粒，Kim等人发现了单个AuNR的最大消光波长与其对周围折射率变化的敏感性之间的相关性。Yi等人11研究了Au纳米颗粒催化还原4-硝基苯酚的光散射光谱的演变，并观察到高折射率细长四面体Au纳米颗粒的电子转移速率比低折射率AuNR的电子转移速率更快。纳米颗粒的大小也影响其性质。例如，在抗体与前列腺特异性抗原修饰的Au纳米颗粒结合的研究中，发现较小的纳米颗粒比较大的纳米颗粒更敏感。12这些结果与极化纳米颗粒的研究一致，例如纳米片13和纳米棒14，其角落和末端对配体结合表现出更高的响应。这些发现表明需要单个纳米颗粒分析。
Consequently, many excellent reviews have been published, covering different aspects of nanomaterials for chemical analysis. 1− 6 The present Review focuses on applications of single nanoparticles in analytical chemistry. Detecting, counting, imaging, and tracking of single nanoparticles represent a critically important capability in analytical chemistry. In addition to revealing basic properties of nanoparticles that could be otherwise washed out in the ensemble analysis of nanoparticles, the capability of single nanoparticle analysis offers many unique applications. Due to limited space, this Review includes mainly works published from 2011 to 2013. Nanoparticles have been used in many analytical assays because of their extraordinary physical and chemical properties.Studies have shown that the physical (eg, light emission and absorption 7) and chemical (eg, catalytic reactions) properties of a nanoparticle depend not only on its chemical composition but also on its size and shape. For example, the optical responses of 10 different gold nanorods (AuNRs) modified with aptamers were found to vary by 3− 4 times. 8 In another study, highly anisotropic nanoparticles were found to be more sensitive to the binding to Hg2+ compared to the isotropic nanoparticles. 9 By analyzing over 100 nanoparticles, Kim et al. 10 discovered a correlation between the maximum extinction wavelength of a single AuNR and its sensitivity to a change in the surrounding refractive index. Yi et al. 11 studied the evolution of optical scattering spectrum of Au nanoparticle-catalyzed reduction of 4-nitrophenol and observed faster electron transfer rates in highindex elongated tetrahexahedral Au nanoparticles compared with those of low-index AuNRs. The size of a nanoparticle also affects its properties. For example, in a study of antibody binding to prostate-specific antigen-modified Au nanoparticles, smaller nanoparticles were found to be more sensitive than the larger nanoparticles. 12 These results were consistent with the study of polarized nanoparticles, such as nanoplates 13 and nanorods, 14 whose corners and ends exhibited higher responses to ligand binding. These findings demonstrate a need for single nanoparticle analysis.
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影响因子：
7.8
作者：
Bruchez, Marcel P.
通讯作者：
Bruchez, Marcel P.
影响因子：
5.7
作者：
Ameen Poyli, M.;Silkin, V. M.;Aizpurua, J.
通讯作者：
Aizpurua, J.
DOI：
10.1523/jneurosci.0048-12.2012
发表时间：
2012-06-27
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Chang JC;Tomlinson ID;Warnement MR;Ustione A;Carneiro AM;Piston DW;Blakely RD;Rosenthal SJ
通讯作者：
Rosenthal SJ
DOI：
10.1073/pnas.0706192104
发表时间：
2007-08-21
影响因子：
11.1
作者：
Cui, Bianxiao;Wu, Chengbiao;Chu, Steven
通讯作者：
Chu, Steven
影响因子：
3.7
作者：
Beeram, Srinivas R.;Zamborini, Francis P.
通讯作者：
Zamborini, Francis P.