Effects of cold air on cardiovascular disease risk factors in rat.
Effects of cold air on cardiovascular disease risk factors in rat.
复制标题
冷空气对大鼠心血管疾病危险因素的影响
DOI：
10.3390/ijerph9072312
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发表时间：
2012-07
影响因子：
--
通讯作者：
Wang B
中科院分区：
文献类型：
--
作者：
Luo B;Zhang S;Ma S;Zhou J;Wang B
本研究的目的是探讨冷空气对大鼠心血管疾病（CVD）风险的潜在影响。健康Wistar大鼠在实验室条件下暴露于人工冷空气中，测定并评价其收缩压、心率、血管收缩、心血管疾病危险因素及心肌损伤指标。治疗组收缩压、全血黏度、血浆去甲肾上腺素、血管紧张素Ⅱ、低密度脂蛋白、总胆固醇、纤维蛋白原水平均显著高于对照组。治疗组与对照组血浆Mb、cTnT及心肌组织无显著差异。结果表明：(1)冷风暴露时血收缩压、WBV、LDL/HDL、总胆固醇（TC）、FG水平升高提示心血管疾病风险升高；(2)冷空气对收缩压及其他心血管疾病危险因素的影响可能持续存在。
The purpose of this study is to explore possible potential implications of cold air in cardiovascular disease (CVD) risk in rats. Healthy Wistar rats were exposed to artificial cold air under laboratory conditions, and their systolic blood pressure, heart rate, vasoconstriction, CVD risk factors, and myocardial damage indicators after cold air exposure were determined and evaluated. Systolic blood pressure, whole blood viscosity, and plasma level of norepinephrine, angiotensinⅡ, low density lipoprotein, total cholesterol, and fibrinogen in treatment groups increased significantly compared with control groups. No significant variations were found in plasma Mb and cTnT and myocardial tissue between the treatment and control groups. Results indicate that: (1) higher levels of SBP, WBV and LDL/HDL, total cholesterol (TC), and FG in blood may indicate higher CVD risks during cold air exposure; (2) cold air may exert continuous impacts on SBP and other CVD risk factors.
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影响因子：
105.7
作者：
KEATINGE, WR;COLESHAW, SRK;CHELLIAH, R
通讯作者：
CHELLIAH, R
影响因子：
4.9
作者：
Kanayama, N;Tsujimura, R;Terao, T
通讯作者：
Terao, T
影响因子：
3
作者：
Li, Yue;Alshaer, Hisham;Fernie, Geoff
通讯作者：
Fernie, Geoff
DOI：
10.1016/j.bbrc.2009.10.082
发表时间：
2009-12-18
影响因子：
3.1
作者：
Guo, Fang;Liu, Juntian;Lu, Peipei
通讯作者：
Lu, Peipei
影响因子：
4.5
作者：
Kysely, Jan;Pokorna, Lucie;Kriz, Bohumir
通讯作者：
Kriz, Bohumir