Development of multisensory integration from the perspective of the individual neuron.

Development of multisensory integration from the perspective of the individual neuron.
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DOI:
10.1038/nrn3742
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发表时间:
2014-08
影响因子:
34.7
通讯作者:
Rowland, Benjamin A.
Rowland, Benjamin A.
中科院分区:
医学1区
文献类型:
--
作者:
Stein, Barry E.;Stanford, Terrence R.;Rowland, Benjamin A.

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协调使用多种感官线索的能力是大脑功能的一个基本方面。它最大限度地利用大脑在任何给定时刻可用的信息,并增强外部事件的生理显著性。因为每一种感官都传达了对外部世界的独特视角,所以跨感官合成信息提供了无法实现的计算优势。多感觉整合不仅具有重要的生存价值,而且还可以创造独特的体验,当来自不同感觉通道的信号结合在一起时就会出现。然而,新生儿大脑中的神经元不能进行多感觉整合,对中脑的研究表明,这一过程的发展不是预先确定的。相反,它的出现和成熟关键取决于跨通道的经验,改变了潜在的神经回路,以这样一种方式,优化多感官整合能力的环境中,动物将发挥作用。
The ability to use cues from multiple senses in concert is a fundamental aspect of brain function. It maximizes the brain’s use of the information available to it at any given moment and enhances the physiological salience of external events. Because each sense conveys a unique perspective of the external world, synthesizing information across senses affords computational benefits that cannot otherwise be achieved. Multisensory integration not only has substantial survival value but can also create unique experiences that emerge when signals from different sensory channels are bound together. However, neurons in a newborn’s brain are not capable of multisensory integration, and studies in the midbrain have shown that the development of this process is not predetermined. Rather, its emergence and maturation critically depend on cross-modal experiences that alter the underlying neural circuit in such a way that optimizes multisensory integrative capabilities for the environment in which the animal will function.
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