Modulation of a neural antigen during metamorphosis in Drosophila melanogaster.

Modulation of a neural antigen during metamorphosis in Drosophila melanogaster.
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果蝇变态过程中神经抗原的调节。

DOI:
10.1016/0012-1606(83)90352-4
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发表时间:
1983
影响因子:
2.7
通讯作者:
Cannon,LE
Cannon,LE
中科院分区:
生物学3区
文献类型:
--
作者:
White,K;Pereira,A;Cannon,LE

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在全变态昆虫的变态过程中,中枢神经系统(CNS)发生了重大的重组(G。Technau和M.海森堡,1982年,《自然》(伦敦)295,405 -407。J. W.杜鲁门和S. E. Reiss,1976,Science192,477-479)。本文用两种特异于果蝇中枢神经系统抗原的单克隆抗体研究了变态期这些神经元抗原的行为。所研究的抗原之一集中在成体和幼虫的CNS的突触区域中。另一种抗原分布更广泛,存在于皮质和突触区域。变态伴随着定位于突触区域的抗原浓度的急剧变化。相反,普遍存在的抗原始终存在。
Major reorganization in the central nervous system (CNS) takes place during metamorphosis in holometabolan insects (G. Technau and M. Heisenberg, 1982,Nature (London)295,405–407. J. W. Truman and S. E. Reiss, 1976,Science192,477–479). In this report, two monoclonal antibodies specific for antigens localized in the CNS ofDrosophila melanogasterare utilized to examine the behavior of these neuronal antigens during metamorphosis. One of the antigens studied is concentrated in synaptic areas of the CNS in adults and larvae. The other antigen is more ubiquitously distributed, being present in both cortical and synaptic regions. Metamorphosis is accompanied by dramatic change in the concentration of the antigen localized to synaptic areas. In contrast, the ubiquitously present antigen persists throughout.
免疫球蛋白 µ 和 γ 重链类别不是由类别特异性 RNA 剪接酶决定的
DOI: 10.1038/274917a0
发表时间: 1978
期刊: Nature
影响因子: 64.8
作者:
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通讯作者: G. Köhler
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