Changes in transmission risk behaviors across stages of HIV disease among people living with HIV.
Changes in transmission risk behaviors across stages of HIV disease among people living with HIV.
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DOI：
10.1016/j.jana.2008.10.005
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发表时间：
2009-01
影响因子：
2
通讯作者：
Kalichman, Seth C.
中科院分区：
文献类型：
--
作者：
Eaton, Lisa A.;Kalichman, Seth C.
艾滋病毒治疗和机会性疾病预防方面的进展大大延长了艾滋病毒/艾滋病感染者的预期寿命。艾滋病毒/艾滋病寿命延长的另一个特点是艾滋病毒传播风险行为的变化。在这里，我们回顾了有关艾滋病毒传播的危险行为的文献，因为它们与艾滋病毒感染者/艾滋病患者的艾滋病毒疾病阶段有关。研究证实，艾滋病毒检测呈阳性之前的一段时间具有高风险行为的特点，表明艾滋病毒在急性感染期间有可能迅速传播。对于许多人来说，在艾滋病毒诊断后立即看到风险行为的减少。然而，这些风险承担的变化并不普遍，在艾滋病毒诊断如何影响风险行为方面存在很大的差异。无症状HIV感染的慢性期通常与某种程度的恢复到高风险行为有关。此外，CD 4计数低于200个细胞/mm 3导致艾滋病的正式诊断，与减少性和药物相关的危险行为有关。因此，针对男女艾滋病毒/艾滋病感染者的减少艾滋病毒风险干预措施需要根据艾滋病毒疾病的阶段进行调整。需要对长期HIV阳性者的危险行为进行进一步研究。
Advances in HIV treatment and opportunistic illness prophylaxis have significantly extended the life expectancy of people living with HIV/AIDS. Increased HIV/AIDS longevity is also marked by changes in HIV transmission risk behaviors. Here we review the literature on HIV transmission risk behaviors as they change in relation to stages of HIV disease among persons who are infected with HIV/AIDS. Studies confirm that the time period immediately preceding testing HIV positive is characterized by high risk behaviors indicating the potential for rapid spread of HIV during acute infection. For many people, reductions in risk behavior are seen immediately following HIV diagnosis. However, these changes in risk taking are not universal and great variability exists in terms of how HIV diagnosis influences risk behaviors. Chronic periods of asymptomatic HIV infection are generally associated with some degree of reverting to high risk behaviors. Also, a CD4 count below 200 cells/mm3 resulting in a formal diagnosis of AIDS, is associated with decreased sexual and drug-related risk behaviors. HIV risk reduction interventions that target men and women living with HIV/AIDS therefore require tailoring to stages of HIV disease. Additional research on risk behaviors of long term HIV positive persons is needed.
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DOI：
10.1097/01.qai.0000230530.02212.86
发表时间：
2006-11-01
影响因子：
3.6
作者：
Drumright, Lydia N.;Little, Susan J.;Gorbach, Pamina M.
通讯作者：
Gorbach, Pamina M.
DOI：
10.1097/01.qai.0000225730.79610.61
发表时间：
2006-08-01
影响因子：
3.6
作者：
Liu, Chenglong;Johnson, Lisette;Jacobson, Lisa P.
通讯作者：
Jacobson, Lisa P.
影响因子：
3.8
作者：
Pinkerton, Steven D.
通讯作者：
Pinkerton, Steven D.
影响因子：
3.8
作者：
Ruiz, L;Romeu, J;Foz, M
通讯作者：
Foz, M
影响因子：
3.2
作者：
Halkitis, PN;Shrem, MT;Wilton, L
通讯作者：
Wilton, L