The Gut Microbiota Influenced by the Intake of Probiotics and Functional Foods with Prebiotics Can Sustain Wellness and Alleviate Certain Ailments like Gut-Inflammation and Colon-Cancer.

The Gut Microbiota Influenced by the Intake of Probiotics and Functional Foods with Prebiotics Can Sustain Wellness and Alleviate Certain Ailments like Gut-Inflammation and Colon-Cancer.
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DOI:
10.3390/microorganisms10030665
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发表时间:
2022-03-20
期刊:
影响因子:
4.5
通讯作者:
Nigam PS
Nigam PS
中科院分区:
生物学3区
文献类型:
--
作者:
Dahiya D;Nigam PS

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肠道微生物群由几种微生物菌株组成,在健康和患病的人中具有多样和可变的组合,在生命的不同阶段发生变化。宿主和肠道微生物之间必须保持健康的平衡,以执行正常的生理,代谢和免疫功能,并防止疾病的发展。各种原因引起的肠道微生物群平衡紊乱引发了一些健康问题,并促进了某些疾病的进展。本综述基于已发表的研究和报告,这些研究和报告描述了益生菌微生物在健康可持续性和减轻某些疾病中的作用。介绍了在食品工业中用作益生菌的GRAS菌株的信息,用于生产发酵乳、酸奶、发酵食品、功能性食品和益生菌饮料。为了保持健康的微生物群,益生菌菌株的冻干活细胞形式的益生菌补充剂也可以以不同的形式提供给消费者。乳酸菌和其他微生物的健康益处及其在控制某些疾病如肠道炎症、糖尿病和肠癌以及保护肠道上皮通透性免受病原体入侵方面的作用进行了讨论。
The gut microbiota is composed of several microbial strains, with diverse and variable combinations in healthy and sick persons, changing at different stages of life. A healthy balance between host and gut microorganisms must be maintained in order to perform the normal physiological, metabolic, and immune functions and prevent disease development. Disturbances in the balance of the gut microbiota by diverse reasons initiate several health issues and promote the progression of certain diseases. This review is based on published research and reports that describe the role of probiotic microorganisms in the sustainability of health and the alleviation of certain diseases. Information is presented on the GRAS strains that are used as probiotics in the food industry for the production of fermented milk, yogurt, fermented food, functional foods, and probiotic drinks. To maintain a healthy microbiota, probiotic supplements in the form of freeze-dried live cells of probiotic strains are also available in different forms to consumers. The health benefits of lactic acid bacteria and other microorganisms and their role in the control of certain diseases such as gut inflammation, diabetes, and bowel cancer and in the safeguarding of the gut epithelial permeability from the invasion of pathogens are discussed.
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