Establishing, maintaining and modifying DNA methylation patterns in plants and animals.
Establishing, maintaining and modifying DNA methylation patterns in plants and animals.
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DOI:
10.1038/nrg2719
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发表时间:
2010-03
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影响因子:
--
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中科院分区:
文献类型:
--
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Cytosine DNA methylation is a stable epigenetic mark that is critical for diverse biological processes including gene and transposon silencing, imprinting, and X chromosome inactivation. Recent findings in plants and animals have greatly increased our understanding of the pathways utilized to accurately target, maintain, and modify patterns of DNA methylation and have revealed unanticipated mechanistic similarities between these organisms. Key roles for small RNAs, proteins with methylated DNA binding domains and DNA glycosylases in these processes have emerged. Drawing on insights from both plants and animals should deepen our understanding of the regulation and biological significance of DNA methylation.
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影响因子:
10.5
作者:
Bartee, L;Malagnac, F;Bender, J
通讯作者:
Bender, J
DOI:
10.1073/pnas.0911640106
发表时间:
2009-12-01
影响因子:
11.1
作者:
Chen, Chen;Jin, Jing;Pawson, Tony
通讯作者:
Pawson, Tony
DOI:
10.1016/s0006-291x(88)80489-3
发表时间:
1988-03-30
影响因子:
3.1
作者:
CANNON, SV;CUMMINGS, A;TEEBOR, GW
通讯作者:
TEEBOR, GW
影响因子:
10.5
作者:
Aravin, Alexei A.;Bourc'his, Deborah
通讯作者:
Bourc'his, Deborah
影响因子:
10.5
作者:
CARLSON, LL;PAGE, AW;BESTOR, TH
通讯作者:
BESTOR, TH