Effect of laparoscopic adjustable gastric banding on metabolic syndrome and its risk factors in morbidly obese adolescents.

Effect of laparoscopic adjustable gastric banding on metabolic syndrome and its risk factors in morbidly obese adolescents.
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DOI:
10.1155/2011/906384
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发表时间:
2011
期刊:
影响因子:
3.3
通讯作者:
Fennoy I
Fennoy I
中科院分区:
其他
文献类型:
--
作者:
Conroy R;Lee EJ;Jean A;Oberfield SE;Sopher A;Kiefer K;Raker C;McMahon DJ;Zitsman JL;Fennoy I

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我们研究了腹腔镜可调节胃束带术(LAGB)对病态肥胖青少年体重减轻、炎症标志物和代谢综合征(MeS)组分的影响,并确定了患有代谢综合征的青少年在LAGB后体重减轻的程度是否低于未患代谢综合征的青少年。在基线、LAGB后6个月和12个月获得14-18岁青少年的数据。在LAGB后6个月和1年观察到显著的体重减轻和MeS组分的改善。6个月后MeS发生率下降56.8%,12个月后下降69.6%。在任何时间点,有和没有MeS的患者LAGB后体重减轻量均无显著差异。检查了基线时有和无MeS的患者体重参数变化与MeS组分之间的相关性,发现其因诊断类别而异。LAGB对病态肥胖青少年的体重、炎症标志物和MeS组分的短期改善有效。
We examined the effect of laparoscopic adjustable gastric banding (LAGB) on weight loss, inflammatory markers, and components of the Metabolic Syndrome (MeS) in morbidly obese adolescents and determined if those with MeS lose less weight post-LAGB than those without. Data from 14–18 yr adolescents were obtained at baseline, 6 and 12 months following LAGB. Significant weight loss and improvements in MeS components were observed 6 months and one year following LAGB. The incidence of MeS declined 56.8% after 6 months and 69.6% after 12 months. There was no significant difference in amount of weight lost post-LAGB between those with and without MeS at either timepoint. Correlations between change in weight parameters and components of MeS in those with and without MeS at baseline were examined and found to vary by diagnostic category. LAGB is effective for short-term improvement in weight, inflammatory markers, and components of MeS in morbidly obese adolescents.
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