Effect of presurgical aerobic exercise on cardiometabolic health 30 days after bariatric surgery.
Effect of presurgical aerobic exercise on cardiometabolic health 30 days after bariatric surgery.
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DOI：
10.14814/phy2.15039
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发表时间：
2021-11
影响因子：
2.5
通讯作者：
Malin SK
中科院分区：
文献类型：
--
作者：
Gilbertson NM;Eichner NZM;Gaitán JM;Khurshid M;Rexrode EA;Kranz S;Hallowell PT;Malin SK
我们评估了术前标准医疗护理（SC）与无监督有氧运动联合SC（EX + SC）对减肥手术后30天心脏代谢健康和生活质量（QoL）的影响。将肥胖患者（n = 14，年龄：42.3 ± 2.5岁，体重指数：45.1 ± 2.5 kg/m2）匹配配对至术前SC（n = 7）或EX + SC（n = 7;步行30分钟/天，5天/周，65-85% HR峰值），持续30天。在手术时（干预后）和术后30天进行身体组成、峰值心肺功能（VO 2 peak）、QoL、炎症（脂联素、瘦素、细胞角蛋白-18）和120分钟混合餐耐受试验，以评估主动脉波形（增强指数，AIx@75）、胰岛素敏感性和葡萄糖总曲线下面积（tAUC）。在术后30天，EX + SC的高分子量（HMW）脂联素（p = 0.01）和HMW与总脂联素的比值（p = 0.04）显著高于SC，尽管它们显著（p = 0.006; ES = 1.86）减少了中度至剧烈体力活动（MVPA）的总时间。术后期间，SC组的VO 2峰值（p = 0.02; ES = 1.54）和120 min AIx@75（p = 0.02; ES = 1.78）的降低幅度显著大于EX + SC组。MVPA的增加与细胞角蛋白-18的减少相关（r =-0.67，p = 0.02）。从手术到术后，VO 2峰值增加与活动/移动性QoL域增加（r = 0.52，p = 0.05）和120 min AIx@75降低（r =-0.61，p = 0.03）相关。在这项初步研究中，术前EX + SC在术后30天没有保持更有利的心脏代谢健康。然而，MVPA的变化似乎对生活质量很重要，应在未来的工作中加以考虑。完成术前有氧运动的患者在手术后没有维持这种行为，与接受标准医疗护理的患者相比，术前运动在术后30天的心脏代谢健康方面没有引起更有利的改善。这项研究表明，增加健身对减肥手术后患者的生活质量很重要。此外，手术后增加身体活动与患者炎症减少有关。
We evaluated the effect of preoperative standard medical care (SC) vs. unsupervised aerobic exercise combined with SC (EX + SC) on cardiometabolic health and quality of life (QoL) 30 days after bariatric surgery. Bariatric patients (n = 14, age: 42.3 ± 2.5 years, body mass index: 45.1 ± 2.5 kg/m2) were match‐paired to presurgical SC (n = 7) or EX + SC (n = 7; walking 30 min/day, 5 day/week, 65–85% HRpeak) for 30 days. Body composition, peak cardiorespiratory fitness (VO2peak), QoL, inflammation (adiponectin, leptin, cytokeratin‐18), and a 120 min mixed meal tolerance test was performed to assess aortic waveforms (augmentation index, AIx@75), insulin sensitivity, and glucose total area under the curve (tAUC) at the time of surgery (post‐intervention) and 30 days post‐surgery. EX + SC had significantly higher high molecular weight (HMW) adiponectin (p = 0.01) and ratio of HMW to total adiponectin (p = 0.04) than SC at 30 days post‐surgery, although they significantly (p = 0.006; ES = 1.86) decreased total time spent in moderate to vigorous physical activity (MVPA). SC had a significantly greater increase in VO2peak (p = 0.02; ES = 1.54) and decrease in 120 min AIx@75 (p = 0.02; ES = 1.78) than EX + SC during the post‐surgical period. The increase in MVPA was associated with a reduction in cytokeratin‐18 (r = −0.67, p = 0.02). Increased VO2peak was associated with increased activity/mobility QoL domain (r = 0.52, p = 0.05) and decreased 120 min AIx@75 (r = −0.61, p = 0.03) from surgery to post‐surgery. Preoperative EX + SC did not maintain more favorable cardiometabolic health 30 days post‐operation in this pilot study. However, changes in MVPA appear important for QoL and should be considered in future work. Patients completing presurgical aerobic exercise did not sustain this behavior after surgery, and preoperative exercise did not cause more favorable improvements in cardiometabolic health 30d postoperation compared to patients receiving standard medical care. This research showed that increased fitness was important for quality of life in patients after bariatric surgery. Further, increased physical activity after surgery was linked to reduced inflammation in patients.
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DOI：
10.1249/mss.0b013e318228bf85
发表时间：
2012-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Kelly, Karen R.;Blaszczak, Alecia;Kirwan, John P.
通讯作者：
Kirwan, John P.
影响因子：
2.9
作者：
Gilbertson NM;Paisley AS;Kranz S;Weltman A;Kirby JL;Hallowell PT;Malin SK
通讯作者：
Malin SK
影响因子：
4.9
作者：
Colley, R. C.;Hills, A. P.;Byrne, N. M.
通讯作者：
Byrne, N. M.
影响因子：
2.9
作者：
Baillot, Aurelie;Vallee, Carol-Anne;Langlois, Marie-France
通讯作者：
Langlois, Marie-France
影响因子：
9
作者：
Karamanakos, Stavros N.;Vagenas, Konstantinos;Alexandrides, Theodore K.
通讯作者：
Alexandrides, Theodore K.