Urinary 1-hydroxypyrene as a biomarker of PAH exposure in 3-year-old Ukrainian children.
Urinary 1-hydroxypyrene as a biomarker of PAH exposure in 3-year-old Ukrainian children.
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DOI：
10.1289/ehp.7898
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发表时间：
2006-04
影响因子：
10.4
通讯作者：
Chislovska N
中科院分区：
文献类型：
--
作者：
Mucha AP;Hryhorczuk D;Serdyuk A;Nakonechny J;Zvinchuk A;Erdal S;Caudill M;Scheff P;Lukyanova E;Shkiryak-Nyzhnyk Z;Chislovska N
Urinary 1-hydroxypyrene (1-OHP) is a biomarker of polycyclic aromatic hydrocarbon (PAH) exposure. We measured urinary 1-OHP in 48 children 3 years of age in Mariupol, Ukraine, who lived near a steel mill and coking facility and compared these with 1-OHP concentrations measured in 42 children of the same age living in the capital city of Kiev, Ukraine. Children living in Mariupol had significantly higher urinary 1-OHP and creatinine-adjusted urinary 1-OHP than did children living in Kiev (adjusted: 0.69 vs. 0.34 μmol/mol creatinine, p < 0.001; unadjusted: 0.42 vs. 0.30 ng/mL, p = 0.002). Combined, children in both cities exposed to environmental tobacco smoke in their homes had higher 1-OHP than did children not exposed (0.61 vs. 0.42 μmol/mol creatinine; p = 0.04; p = 0.07 after adjusting for city). In addition, no significant differences were seen with sex of the children. Our sample of children in Mariupol has the highest reported mean urinary 1-OHP concentrations in children studied to date, most likely due to their proximity to a large industrial point source of PAHs.
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DOI：
10.1007/s004200100239
发表时间：
2001-08-01
影响因子：
3
作者：
Fiala, Z;Vyskocil, A;Emminger, S
通讯作者：
Emminger, S
影响因子：
4.3
作者：
Vyskocil, A;Fiala, Z;Emminger, S
通讯作者：
Emminger, S
影响因子：
9.8
作者：
Siwinska, E;Mielzynska, D;Kwapulinski, J
通讯作者：
Kwapulinski, J
影响因子：
10.4
作者：
vanWijnen, JH;Slob, R;Woudenberg, F
通讯作者：
Woudenberg, F
DOI：
10.1007/s004200050216
发表时间：
1997-10-01
影响因子：
3
作者：
Brzeznicki, S;Jakubowski, M;Czerski, B
通讯作者：
Czerski, B