Masquerade Syndromes: Malignancies Mimicking Inflammation in the Eye
Masquerade Syndromes: Malignancies Mimicking Inflammation in the Eye
复制标题
假面舞会综合症：模仿眼部炎症的恶性肿瘤
DOI：
10.1097/00004397-200201000-00016
复制
发表时间：
2002
影响因子：
--
通讯作者：
J. O'Brien
中科院分区：
文献类型：
--
作者：
Tony Tsai;J. O'Brien
伪装综合征一词最早出现在1967年的眼科文献中，用来描述一种表现为慢性结膜炎的结膜癌。从那时起，化妆综合症的标签被贴上了一组模仿眼部炎症性疾病的疾病。虽然一些良性疾病可以被认为是伪装综合征，但大多数情况下这个术语指的是恶性实体。眼肿瘤学是一门专门研究眼部和眼眶恶性肿瘤的专科，本质上是一种罕见疾病。因此，对伪装综合征的讨论变成了对罕见疾病的罕见表现的研究。然而，这个问题值得广泛关注，因为在许多情况下，伪装的疾病不仅威胁视力，而且可能致命。通过及早识别和诊断化妆舞会，可以避免严重的发病率和死亡率。只有当考官熟悉这些不常见的陈述并保持适当的怀疑指数时，才能达到这一终点。这篇简短的综述集中于六种可以伪装成眼部炎症的恶性疾病：皮脂腺癌、眼内淋巴瘤、眼周淋巴瘤、视网膜母细胞瘤、眼部黑色素瘤和眼转移瘤。目的是强调流行病学和临床特征，这些特征应该引起检查人员对伪装综合征的怀疑，然后强调可能有助于诊断的操作。为简洁起见，避免了关于治疗选择的讨论。对于这六种和许多较罕见的伪装综合征，治疗成功的最佳初始步骤是早期明确诊断。
The term masquerade syndrome first appeared in the ophthalmic literature in 1967 to describe a conjunctival carcinoma that had presented as chronic conjunctivitis. Since then, the masquerade syndrome label has been applied to a group of disorders that mimic ocular inflammatory disease. Although some benign conditions can be considered masquerade syndromes, most often the term refers to malignant entities. Ocular oncology, the subspecialty that concerns itself with ocular and orbital malignancies, is by nature a field of uncommon disorders. A discussion of the masquerade syndromes, therefore, becomes a study in uncommon presentations of uncommon diseases. Nevertheless, the subject deserves wide attention because, in many cases, the diseases that masquerade are not only vision-threatening but potentially fatal. Significant morbidity and mortality can be averted by early recognition and diagnosis of the masquerade. This end point can be achieved only when an examiner is familiar with these uncommon presentations and maintains an appropriate index of suspicion. This brief review concentrates on six malignant conditions that can masquerade as ocular inflammation: sebaceous gland carcinoma, intraocular lymphoma, periocular lymphoma, retinoblastoma, ocular melanoma, and ocular metastases. The aim is to emphasize epidemiological and clinical features that should raise an examiner’s suspicion for a masquerade syndrome and then to highlight maneuvers that may assist in making the diagnosis. For brevity, discussions regarding therapeutic choices have been avoided. For these six and many of the rarer masquerade syndromes, the best initial step to therapeutic success is early definitive diagnosis.
葡萄膜恶性黑色素瘤与眼部和眼真皮黑色素细胞增多症相关。
影响因子：
13.7
作者：
Gonder,JR;Shields,JA;Albert,DM;Augsburger,JJ;Lavin,PT
通讯作者：
Lavin,PT
玻璃体内大细胞淋巴瘤。
影响因子：
8.9
作者：
Buettner,H;Bolling,JP
通讯作者：
Bolling,JP
巩膜炎是脉络膜恶性黑色素瘤的首发表现。
影响因子：
13.7
作者：
Yap,EY;Robertson,DM;Buettner,H
通讯作者：
Buettner,H