Regulation of lipid homeostasis by the bifunctional SREBF2-miR33a locus.

Regulation of lipid homeostasis by the bifunctional SREBF2-miR33a locus.
复制标题

DOI:
10.1016/j.cmet.2011.02.004
复制
发表时间:
2011-03-02
期刊:
影响因子:
29
通讯作者:
MacDougald OA
MacDougald OA
中科院分区:
生物学1区
文献类型:
--
作者:
Bommer GT;MacDougald OA

文献摘要

参考文献

被引文献

相似文献

固醇调节元件结合因子-2(SREBF 2)基因是编码SREBP-2和microRNA-33 a的双功能基因座,SREBP-2是参与胆固醇生物合成的基因的众所周知的转录调节因子,microRNA-33 a最近已显示出减少参与胆固醇输出和脂肪酸的β-氧化的蛋白质的表达,从而为脂质稳态的调节增加了意想不到的复杂性和微调层。
The sterol regulatory element-binding factor-2 (SREBF2) gene is a bifunctional locus encoding SREBP-2, a well-known transcriptional regulator of genes involved in cholesterol biosynthesis, and microRNA-33a, which has recently been shown to reduce expression of proteins involved in export of cholesterol and β-oxidation of fatty acids, thus adding an unexpected layer of complexity and fine-tuning to regulation of lipid homeostasis.
DOI: 10.1038/nature07242
发表时间: 2008-09-04
期刊: NATURE
影响因子: 64.8
作者:
Baek, Daehyun;Villen, Judit;Shin, Chanseok;Camargo, Fernando D.;Gygi, Steven P.;Bartel, David P.
通讯作者: Bartel, David P.
DOI: 10.1126/science.1189123
发表时间: 2010-06-18
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Najafi-Shoushtari SH;Kristo F;Li Y;Shioda T;Cohen DE;Gerszten RE;Näär AM
通讯作者: Näär AM
DOI: 10.1621/nrs.08002
发表时间: 2010-04-16
期刊: Nuclear receptor signaling
影响因子: --
作者:
Pyper, Sean R;Viswakarma, Navin;Reddy, Janardan K
通讯作者: Reddy, Janardan K
DOI: 10.1074/jbc.m110.152090
发表时间: 2010-10-29
影响因子: 4.8
作者:
Gerin, Isabelle;Clerbaux, Laure-Alix;Bommer, Guido T.
通讯作者: Bommer, Guido T.
DOI: 10.1126/science.1071124
发表时间: 2002-05-03
期刊: SCIENCE
影响因子: 56.9
作者:
Dobrosotskaya, IY;Seegmiller, AC;Rawson, RB
通讯作者: Rawson, RB