Regulation of lipid homeostasis by the bifunctional SREBF2-miR33a locus.
Regulation of lipid homeostasis by the bifunctional SREBF2-miR33a locus.
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DOI:
10.1016/j.cmet.2011.02.004
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发表时间:
2011-03-02
期刊:
影响因子:
29
通讯作者:
MacDougald OA
中科院分区:
文献类型:
--
作者:
Bommer GT;MacDougald OA
The sterol regulatory element-binding factor-2 (SREBF2) gene is a bifunctional locus encoding SREBP-2, a well-known transcriptional regulator of genes involved in cholesterol biosynthesis, and microRNA-33a, which has recently been shown to reduce expression of proteins involved in export of cholesterol and β-oxidation of fatty acids, thus adding an unexpected layer of complexity and fine-tuning to regulation of lipid homeostasis.
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影响因子:
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通讯作者:
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DOI:
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期刊:
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影响因子:
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通讯作者:
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