Non-spin-echo 3D transverse hadamard encoded proton spectroscopic imaging in the human brain.
Non-spin-echo 3D transverse hadamard encoded proton spectroscopic imaging in the human brain.
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DOI：
10.1002/mrm.24464
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发表时间：
2013-07
影响因子：
3.3
通讯作者：
Gonen, Oded
中科院分区：
文献类型：
--
作者：
Cohen, Ouri;Tal, Assaf;Goelman, Gadi;Gonen, Oded
A non-spin-echo multivoxel proton MR localization method based on three dimensional (3D) transverse Hadamard spectroscopic imaging (T-HSI) is introduced and demonstrated in a phantom and the human brain. Spatial encoding is achieved with three selective 90° radio-frequency pulses along perpendicular axes: The first two create a longitudinal ±MZ Hadamard order in the volume of interest (VOI). The third pulse spatially Hadamard-encodes the ±MZs in the VOI in the third direction while bringing them to the transverse plane to be acquired immediately. The approaching-ideal point spread function (PSF) of Hadamard encoding and very short acquisition delay yield signal-to-noise-ratios of 20±8, 23±9 and 31±10 for choline, creatine and N-acetylaspartate in the human brain at 1.5 T from 1 cm3 voxels in 21 minutes. The advantages of T HSI are that unlike gradient (Fourier) phase-encoding: (i) the VOI does not need to be smaller than the field-of-view to prevent aliasing; (ii) the number of partitions in each direction can be small, 8, 4 or even 2 at no cost in PSF; (iii) the VOI does not have to be contiguous; and (iv) the voxel profile depends on the available B1 and pulse synthesis paradigm and can therefore, at least theoretically, approach “ideal” “1” inside and “0” elsewhere.
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影响因子：
3.3
作者：
Fleysher, Lazar;Fleysher, Roman;Liu, Songtao;Gonen, Oded
通讯作者：
Gonen, Oded
影响因子：
--
作者：
Bloch, F;Siegert, A
通讯作者：
Siegert, A
影响因子：
2.9
作者：
BROWN, TR
通讯作者：
BROWN, TR
影响因子：
2.2
作者：
FRAHM, J;MERBOLDT, KD;HANICKE, W
通讯作者：
HANICKE, W
影响因子：
3.3
作者：
Girard, N;Fogliarini, C;Cozzone, P
通讯作者：
Cozzone, P