A concise overview of circadian timing in Drosophila.
A concise overview of circadian timing in Drosophila.
复制标题
果蝇昼夜节律的简明概述。
DOI:
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发表时间:
2003
期刊:
影响因子:
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通讯作者:
R. Costa
中科院分区:
文献类型:
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作者:
M. Zordan;F. Sandrelli;R. Costa
The molecular aspects of circadian rhythmicity in Drosophila melanogaster are reviewed, with particular regard to the core of the master oscillator and the light signalling input pathway. The core is schematically represented as consisting of two interlocking transcriptional feedback loops based principally on the clock genes period, timeless, clock and cycle and their products which, through the interaction with other partners, give rise to a stable 24h endogenous oscillator. Light signalling to the clock is multifaceted and is still the subject of much speculation and research. Here we review data essentially regarding the role of the clock protein Timeless and its interaction with the photopigment Cryptochrome.
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