Enteral Feeding Practices for Very Preterm and Very Low Birth Weight Infants in Nigeria and Kenya.

Enteral Feeding Practices for Very Preterm and Very Low Birth Weight Infants in Nigeria and Kenya.
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DOI:
10.3389/fped.2022.892209
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发表时间:
2022
影响因子:
2.6
通讯作者:
Allen, Stephen J.
Allen, Stephen J.
中科院分区:
医学3区
文献类型:
--
作者:
Tongo, Olukemi O.;Olwala, Macrine A.;Talbert, Alison W.;Nabwera, Helen M.;Akindolire, Abimbola E.;Otieno, Walter;Nalwa, Grace M.;Andang'o, Pauline E. A.;Mwangome, Martha K.;Abdulkadir, Isa;Ezeaka, Chinyere V.;Ezenwa, Beatrice N.;Fajolu, Iretiola B.;Imam, Zainab O.;Umoru, Dominic D.;Abubakar, Ismaela;Embleton, Nicholas D.;Allen, Stephen J.

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优化极早产儿(妊娠28-32周)和极低出生体重儿(VLBW; 1,000 g至<1,500 g)的营养有可能改善他们的生存,生长和长期健康结果。评估尼日利亚和肯尼亚极早产儿和极低出生体重新生儿的喂养实践。这是一项横断面研究,采用方便抽样。向尼日利亚和肯尼亚在新生儿病房工作的医生发送了一份标准问卷。在50名受访者中,37名(74.0%)来自尼日利亚,13名(26.0%)来自肯尼亚。所有患者均开始母乳喂养,24例(48.0%)在24 h内开始。只有28人(56.0%)使用书面喂养指南。起始体积范围为10至80 ml/kg/天。中位喂养量增加为20 ml/kg/天(IQR 10-20),婴儿在8天内达到完全喂养(IQR 6-12)。26个(52.0%)单位每隔2小时喂养婴儿。7个单位(14.0%)进行母乳强化,而叶酸、铁、钙和磷分别在42个(84.0%)、36个(72.0%)、22个(44.0%)、5个(10.0%)单位中处方。没有一个单位可以获得捐赠母乳,只有18个单位(36.0%)有储存挤出母乳的设施。12例(24.0%)使用奶妈,30例(60.0%)使用配方饲料。在尼日利亚和肯尼亚,极早产儿和极低出生体重儿的喂养方法差异很大,可能是因为缺乏当地产生的证据。在人力资源、技术和消耗品有限的情况下,迫切需要高质量的研究来指导这些婴儿的喂养。
Optimizing nutrition in very preterm (28–32 weeks gestation) and very low birth weight (VLBW; 1,000 g to <1,500 g) infants has potential to improve their survival, growth, and long-term health outcomes. To assess feeding practices in Nigeria and Kenya for very preterm and VLBW newborn infants. This was a cross-sectional study where convenience sampling was used. A standard questionnaire was sent to doctors working in neonatal units in Nigeria and Kenya. Of 50 respondents, 37 (74.0%) were from Nigeria and 13 (26.0%) from Kenya. All initiated enteral feeds with breastmilk, with 24 (48.0%) initiating within 24 h. Only 28 (56.0%) used written feeding guidelines. Starting volumes ranged between 10 and 80 ml/kg/day. Median volume advancement of feeds was 20 ml/kg/day (IQR 10–20) with infants reaching full feeds in 8 days (IQR 6–12). 26 (52.0%) of the units fed the infants 2 hourly. Breastmilk fortification was practiced in 7 (14.0%) units, while folate, iron, calcium, and phosphorus were prescribed in 42 (84.0%), 36 (72.0%), 22 (44.0%), 5 (10.0%) of these units, respectively. No unit had access to donor breastmilk, and only 18 (36.0%) had storage facilities for expressed breastmilk. Twelve (24.0%) used wet nurses whilst 30 (60.0%) used formula feeds. Feeding practices for very preterm and VLBW infants vary widely within Nigeria and Kenya, likely because of lack of locally generated evidence. High quality research that informs the feeding of these infants in the context of limited human resources, technology, and consumables, is urgently needed.
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