The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review.
The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review.
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DOI：
10.1186/s12985-017-0877-3
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发表时间：
2017-11-10
期刊：
影响因子：
4.8
通讯作者：
Melhem NM
中科院分区：
文献类型：
--
作者：
Kreidieh K;Charide R;Dbaibo G;Melhem NM
诺如病毒（NoV）被认为是病毒性急性胃肠炎（AGE）的第二大病因。据我们所知，目前尚无系统评价评估中东和北非（MENA）地区NOV在AGE中的作用。因此，我们对过去15年（2000-2015年）MENA地区24个国家研究NoV的文章进行了广泛的系统性文献综述。方法和报告是根据2015 PRISMA-P并基于国际前瞻性系统评价登记系统（PROSPERO）的要素设定的。我们检索了38项符合预定义纳入标准的研究，并用于提取完整数据。在该区域24个国家中的15个国家进行了关于新型流感病毒的研究。报告的中东和北非国家的新冠病毒感染率在0.82%至36.84%之间。大多数研究是临床观察性研究，主要在儿童中评估NoV发生率。参与者是从门诊和门诊招募的。全年都有NoV感染的报告，主要在寒冷的月份观察到高峰。GII.4是参与者粪便中检测到的主要基因型，25项研究中有16项（64%）报告。总体而言，人们越来越认识到，在中东和北非地区的所有年龄组中，NOV是AGE的重要致病因素。需要进一步研究以评估不同年龄组之间的国家和区域NOV负担，其分子多样性和季节性变化。
Norovirus (NoV) is considered the second leading cause of viral acute gastroenteritis (AGE). To our knowledge, there are no systematic reviews assessing the role of NoV in AGE in the Middle East and North Africa (MENA) region. Consequently, we conducted an extensive systematic literature review on articles studying NoV in the 24 countries of the MENA region during the past 15 years (2000-2015). The methods and reporting were set according to the 2015 PRISMA-P and based on the elements from the international prospective register of systematic reviews (PROSPERO). We retrieved 38 studies meeting our predefined inclusion criteria and were used to extract full data. Studies reporting on NoV were conducted in 15 out of the 24 countries of the region. The reported NoV infection rates in MENA countries ranged between 0.82% and 36.84%. The majority of studies were clinical observational studies assessing NoV rates mainly among children. Participants were recruited from in- and outpatient clinics. NoV infection was reported all year round with with peaks observed mainly during cold months. GII.4 was the predominant genotype detected in stool of participants as reported by 16 out of 25 studies (64%). Overall, there is an increasing recognition of NoV as an important causative agent of AGE across all age groups in the MENA region. Further studies are needed to assess the national and the regional burden of NoV among different age groups, its molecular diversity and seasonal variability.
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DOI：
10.1016/s1473-3099(14)70767-4
发表时间：
2014-08
期刊：
The Lancet. Infectious diseases
影响因子：
--
作者：
Ahmed SM;Hall AJ;Robinson AE;Verhoef L;Premkumar P;Parashar UD;Koopmans M;Lopman BA
通讯作者：
Lopman BA
影响因子：
12.7
作者：
Al-Mashhadani, Manar Najim;Nakagomi, Osamu;Cumliffe, Nigel A.
通讯作者：
Cumliffe, Nigel A.
影响因子：
3.7
作者：
Ahmed SM;Lopman BA;Levy K
通讯作者：
Levy K
影响因子：
3.1
作者：
Arias A;Emmott E;Vashist S;Goodfellow I
通讯作者：
Goodfellow I
影响因子：
12.7
作者：
Al-Rashidi, Amirah;Chehadeh, Wassim;Albert, M. John
通讯作者：
Albert, M. John