Tissue morphodynamics: Translating planar polarity cues into polarized cell behaviors.
Tissue morphodynamics: Translating planar polarity cues into polarized cell behaviors.
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DOI:
10.1016/j.semcdb.2016.03.012
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发表时间:
2016-07
影响因子:
7.3
通讯作者:
Devenport, Danelle
中科院分区:
文献类型:
--
作者:
Devenport, Danelle
关键词:
The ability of cells to collectively orient and align their behaviors is essential in multicellular organisms for unidirectional cilia beating, collective cell movements, oriented cell divisions, and asymmetric cell fate specification. The planar cell polarity pathway coordinates a vast and diverse array of collective cell behaviors by intersecting with downstream pathways that regulate cytoskeletal dynamics and intercellular signaling. How the planar polarity pathway translates directional cues to produce polarized cell behaviors is the focus of this review.
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