Influence of Alcohol Consumption on the Development of Erosive Esophagitis in Both Sexes: A Longitudinal Study.
Influence of Alcohol Consumption on the Development of Erosive Esophagitis in Both Sexes: A Longitudinal Study.
复制标题
DOI：
10.3390/nu14224760
复制
发表时间：
2022-11-10
期刊：
影响因子：
5.9
通讯作者：
Takayama T
中科院分区：
文献类型：
--
作者：
Sogabe M;Okahisa T;Kagawa M;Ueda H;Kagemoto K;Tanaka H;Kida Y;Tomonari T;Taniguchi T;Miyamoto H;Sato Y;Nakasono M;Takayama T
饮酒量的变化对两种性别糜烂性食管炎（EE）发展的影响尚不清楚。这项观察性研究调查了饮酒对EE发展影响的性别差异，并纳入了2582名基线时没有EE的患者，这些患者来自13，448名在> 1年内接受> 2次健康检查的患者。在男性和女性中，开始饮酒的不饮酒者和戒酒、增加和减少每周饮酒量的饮酒者的比例分别为7.2%、9.7%、14.7%和24.1%和7.3%、17.8%、12.8%和39.0%。在最后一个队列中，211/1405（15.0%）男性和79/1177（6.7%）女性新发EE。男性和女性中饮酒在EE发生中的比值比（OR）分别为1.252（95% CI，0.907 - 1.726）和1.078（95% CI，0.666 - 1.747）。在年龄<50岁的男性中，饮酒≥ 70 g/周发生EE的OR为2.825（95% CI，1.427 - 5.592），而在女性中，饮酒≥ 140 g/周发生EE的OR为3.248（95% CI，1.646 - 6.410）。在年龄<50岁的参与者中，男性和女性中每日饮酒在EE发展中的OR分别为2.692（95%CI，1.298 - 5.586）和4.030（95%CI，1.404 - 11.57）。饮酒对EE发展的影响在性别之间存在差异。我们建议50岁以下的人不要饮酒，以避免EE的发展。每日饮酒者应评估EE的发展。
The influence of changes in alcohol consumption on erosive esophagitis (EE) development in both sexes is unclear. This observational study investigated sex differences in the influence of alcohol consumption on EE development, and included 2582 patients without EE at baseline from 13,448 patients who underwent >2 health check-ups over >1 year. The rates of non-drinkers who started drinking, and drinkers who abstained from drinking, who increased, and who decreased their weekly alcohol consumption were 7.2%, 9.7%, 14.7%, and 24.1% and 7.3%, 17.8%, 12.8%, and 39.0% in men and women, respectively. In the final cohort, 211/1405 (15.0%) men and 79/1177 (6.7%) women newly developed EE. The odds ratio (OR) for drinking in EE development was 1.252 (95% confidence interval (CI), 0.907–1.726) among men and 1.078 (95% CI, 0.666–1.747) among women. Among men aged <50 years, the OR for drinking ≥70 g/week in EE development was 2.825 (95% CI, 1.427–5.592), whereas among women, the OR for drinking ≥140 g/week in EE development was 3.248 (95% CI, 1.646–6.410). Among participants aged <50 years, the OR for daily drinking in EE development was 2.692 (95% CI, 1.298–5.586) among men and 4.030 (95% CI, 1.404–11.57) among women. The influence of alcohol consumption on EE development differed between the sexes. We recommend no alcohol consumption for individuals aged <50 years to avoid EE development. Daily drinkers should be assessed for EE development.
登录
查看更多内容
胃食管反流病流行病学最新进展：系统评价。
影响因子：
24.5
作者：
El-Serag HB;Sweet S;Winchester CC;Dent J
通讯作者：
Dent J
影响因子：
10.3
作者：
Gammon, MD;Schoenberg, JB;Fraumeni, JF
通讯作者：
Fraumeni, JF
影响因子：
29.4
作者：
Anderson, Lesley A.;Cantwell, Marie M.;Murray, Liam J.
通讯作者：
Murray, Liam J.
影响因子：
2.6
作者：
Park, C. H.;Kim, K. O.;Kim, H. Y.
通讯作者：
Kim, H. Y.
影响因子：
3.4
作者：
Toki Y;Yamauchi R;Kayashima E;Adachi K;Kishi K;Suetsugu H;Wada T;Endo H;Yamada H;Osaga S;Kamiya T;Nakada K;Iwakiri K;Haruma K;Joh T
通讯作者：
Joh T