On the role of the ventromedial prefrontal cortex in self-processing: the valuation hypothesis.
On the role of the ventromedial prefrontal cortex in self-processing: the valuation hypothesis.
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DOI：
10.3389/fnhum.2013.00372
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发表时间：
2013
影响因子：
2.9
通讯作者：
D'Argembeau A
中科院分区：
文献类型：
--
作者：
D'Argembeau A
随着功能神经成像的发展，在识别参与自我相关加工的大脑区域方面取得了重要进展。最一致的发现之一是，当人们思考自己和生活的各个方面时，腹内侧额前皮质(VmPFC)被激活，例如他们的特征、经历、偏好、能力和目标。最近的证据表明，这个区域可能不支持自我反省本身的行为，但其在自我加工中的确切功能仍不清楚。在这篇文章中，我检验了一种假设，即vmPFC可能有助于将个人价值或意义赋予与自我相关的内容：涉及或与自我相关的刺激和心理表征往往被赋予独特的价值或意义，而vmPFC的功能可能恰恰是评估或代表这种意义。尽管到目前为止，直接验证这一假说的研究相对较少，但有几条证据表明，自我加工过程中vmPFC的活动取决于自我相关内容的个人意义。首先，与自我表征的心理距离增加会导致vmPFC中的激活减少。其次，vmPFC的激活程度与归因于自我表征的个人重要性呈线性关系。第三，vmPFC的活动受到个体对自我反思兴趣的差异的影响。最后，证据表明，vmPFC对自我的外在方面做出反应，这些外在方面具有很高的个人价值，例如财产和亲密的他人。通过将个人价值赋予与自我相关的内容，vmPFC可能在自我表征的构建、稳定和修改中发挥重要作用，并最终指导我们的选择和决定。
With the development of functional neuroimaging, important progress has been made in identifying the brain regions involved in self-related processing. One of the most consistent findings has been that the ventromedial prefrontal cortex (vMPFC) is activated when people contemplate various aspects of themselves and their life, such their traits, experiences, preferences, abilities, and goals. Recent evidence suggests that this region may not support the act of self-reflection per se, but its precise function in self-processing remains unclear. In this article, I examine the hypothesis that the vMPFC may contribute to assign personal value or significance to self-related contents: stimuli and mental representations that refer or relate to the self tend to be assigned unique value or significance, and the function of the vMPFC may precisely be to evaluate or represent such significance. Although relatively few studies to date have directly tested this hypothesis, several lines of evidence converge to suggest that vMPFC activity during self-processing depends on the personal significance of self-related contents. First, increasing psychological distance from self-representations leads to decreased activation in the vMPFC. Second, the magnitude of vMPFC activation increases linearly with the personal importance attributed to self-representations. Third, the activity of the vMPFC is modulated by individual differences in the interest placed on self-reflection. Finally, the evidence shows that the vMPFC responds to outer aspects of self that have high personal value, such as possessions and close others. By assigning personal value to self-related contents, the vMPFC may play an important role in the construction, stabilization, and modification of self-representations, and ultimately in guiding our choices and decisions.
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DOI：
10.1177/1073858411403316
发表时间：
2012-06
期刊：
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
影响因子：
--
作者：
Andrews-Hanna JR
通讯作者：
Andrews-Hanna JR
影响因子：
1.1
作者：
Bechara, A;Damasio, AR
通讯作者：
Damasio, AR
影响因子：
4.2
作者：
Brosch, Tobias;Coppin, Geraldine;Sander, David
通讯作者：
Sander, David
影响因子：
5.7
作者：
D'Argembeau, A;Collette, F;Salmon, E
通讯作者：
Salmon, E
影响因子：
2.5
作者：
Andrews-Hanna, Jessica R.;Reidler, Jay S.;Buckner, Randy L.
通讯作者：
Buckner, Randy L.