Sex Differences in the Association Between Poor Sleep Quality and Alcohol-Related Problems Among Heavy Drinkers With Insomnia.
Sex Differences in the Association Between Poor Sleep Quality and Alcohol-Related Problems Among Heavy Drinkers With Insomnia.
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DOI：
10.3389/fnbeh.2022.875168
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发表时间：
2022
影响因子：
3
通讯作者：
Weafer, Jessica
中科院分区：
文献类型：
--
作者：
Verlinden, Justin J.;Moloney, Mairead E.;Whitehurst, Lauren N.;Weafer, Jessica
酒精使用障碍(AUD)和失眠高度共存；至少40%的AUD患者患有失眠。女性比男性更容易报告失眠，近年来AUD的发病率出现了令人担忧的上升。因此，AUD和失眠之间的联系在女性中可能尤其明显。然而，目前对这种关联中的性别差异知之甚少。在这里，我们研究了饮酒和睡眠质量之间的关系在女性和男性之间的不同程度。大量饮酒的女性(n=66)和男性(n=45)完成了匹兹堡睡眠质量指数(PSQI)来评估睡眠质量，以及酒精使用障碍识别测试(AUDIT)来评估酒精使用和酒精相关问题。通过分层回归分析来确定睡眠质量差与酒精相关问题之间的关联的性别差异。在控制了年龄、整体主观压力和抑郁之后，性行为显著缓和了睡眠质量差和酒精相关问题之间的正相关关系。对每个性别的简单斜率的进一步分析表明，较差的睡眠质量(即PSQI得分较高)与女性更严重的酒精相关问题(即审计得分较高)有关，但男性没有。这些结果表明，在酗酒并失眠的人中，女性睡眠不佳与饮酒问题的相关性比男性更强。需要进一步的研究来研究这种关系背后的潜在机制。具体地说，确定酗酒女性的睡眠问题是酗酒的原因还是后果，还是两者兼而有之，这一点非常重要。
Alcohol Use Disorder (AUD) and insomnia are highly comorbid; at least 40% of individuals with AUD suffer from insomnia. Women are more likely to report insomnia than men and have seen a concerning rise in rates of AUD in recent years. As such, the association between AUD and insomnia could be particularly pronounced in women. However, currently little is known regarding sex differences in this association. Here we examined the degree to which relationships between alcohol use and sleep quality differ between women and men. Heavy drinking women (n = 66) and men (n = 45) completed the Pittsburgh Sleep Quality Index (PSQI) to assess sleep quality and the Alcohol Use Disorders Identification Test (AUDIT) to assess alcohol use and alcohol-related problems. Hierarchical regression analyses were conducted to determine sex differences in the association between poor sleep quality and alcohol-related problems. After controlling for age, global subjective stress, and depression, sex significantly moderated the positive association between poor sleep quality and alcohol-related problems. Further analyses of the simple slopes for each sex revealed that poorer sleep quality (i.e., higher scores on the PSQI) were associated with greater alcohol-related problems (i.e., higher scores on the AUDIT) in women, but not in men. These results suggest that in heavy drinkers with insomnia, poor sleep is more strongly associated with drinking problems in women than in men. Future research is needed to investigate potential mechanisms underlying this relationship. Specifically, it will be important to determine whether sleep problems in heavy drinking women are a cause or consequence, or both, of heavy drinking.
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
1.7
作者：
Ogeil, Rowan P.;Phillips, James G.;Broadbear, Jillian H.
通讯作者：
Broadbear, Jillian H.
DOI：
10.1111/j.1530-0277.2010.01417.x
发表时间：
2011-05
期刊：
Alcoholism, clinical and experimental research
影响因子：
--
作者：
Arnedt JT;Rohsenow DJ;Almeida AB;Hunt SK;Gokhale M;Gottlieb DJ;Howland J
通讯作者：
Howland J
影响因子：
13.5
作者：
Breese, George R.;Sinha, Rajita;Heilig, Markus
通讯作者：
Heilig, Markus
影响因子：
4.8
作者：
Bastien, Celyne H.;Vallieres, Annie;Morin, Charles M.
通讯作者：
Morin, Charles M.