Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices.

Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices.
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焦耳热对基于绝缘体的介电泳装置中粒子固定的影响。

DOI:
10.1002/elps.201300171
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发表时间:
2014-02
期刊:
影响因子:
2.9
通讯作者:
Davalos, Rafael V.
Davalos, Rafael V.
中科院分区:
生物学3区
文献类型:
--
作者:
Gallo-Villanueva, Roberto C.;Sano, Michael B.;Lapizco-Encinas, Blanca H.;Davalos, Rafael V.

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在这项工作中,针对用于基于绝缘体的介电电泳 (iDEP) 的具有圆柱形绝缘柱的微通道,研究了通过施加直流电势获得的焦耳热引起的温度效应。悬浮介质的电导率、局部电场和平方电场梯度直接影响施加在颗粒上的介电泳力的大小,我们使用 COMSOL Multiphysics 进行了计算模拟。据观察,沿微通道形成温度梯度,其重新分布悬浮介质的电导率,导致介电泳力朝向通道入口增加,同时朝向出口减小。实验结果与预期的颗粒捕获区域的模拟结果非常吻合。这项研究证明了在设计 iDEP 系统时考虑焦耳热效应的重要性。
In this work, the temperature effects due to Joule heating obtained by application of a DC electric potential were investigated for a microchannel with cylindrical insulating posts employed for insulator based dielectrophoresis (iDEP). The conductivity of the suspending medium, the local electric field, and the gradient of the squared electric field, which directly affect the magnitude of the dielectrophoretic force exerted on particles, were computationally simulated employing COMSOL Multiphysics. It was observed that a temperature gradient is formed along the microchannel which redistributes the conductivity of the suspending medium leading to an increase of the dielectrophoretic force towards the inlet of the channel while decreasing towards the outlet. Experimental results are in good agreement with simulations on the particle trapping zones anticipated. This study demonstrates the importance of considering Joule heating effects when designing iDEP systems.
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