Worldwide trends in esophageal cancer survival, by sub-site, morphology, and sex: an analysis of 696,974 adults diagnosed in 60 countries during 2000-2014 (CONCORD-3).
Worldwide trends in esophageal cancer survival, by sub-site, morphology, and sex: an analysis of 696,974 adults diagnosed in 60 countries during 2000-2014 (CONCORD-3).
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DOI：
10.1002/cac2.12457
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发表时间：
2023-09
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影响因子：
--
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中科院分区：
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食管癌的存活率在世界范围内都很低，尽管存在一些差异。解剖亚位和形态亚型分布的差异可能有助于解释所有食管癌生存率的国际差异。我们通过解剖亚位和形态学亚型来估计生存率，以进一步了解地形和形态学对食管癌生存的国际比较的影响。我们对60个参与研究的国家中诊断为食管癌的成年人（15 - 99岁）的年龄标准化1年和5年净生存率进行了估计，以监测诊断日历期（2000 - 2004年、2005 - 2009年、2010 - 2014年）、亚部位、形态和性别的生存趋势。在2010 - 2014年诊断的成年人中，食管下三分之一的肿瘤最常见，其次是重叠亚位和未指定亚位的肿瘤。在2010 - 2014年期间，鳞状细胞癌的诊断比例在亚洲国家普遍较高（50% - 90%），而腺癌在欧洲、北美和大洋洲更为常见（50% - 60%）。从2000 - 2004年到2010 - 2014年，鳞状细胞癌的比例普遍下降，腺癌的比例上升。随着时间的推移，每个亚部位的年龄标准化5年生存率几乎没有改善。日本鳞状细胞癌（67.7%）和腺癌（69.0%）的年龄标准化一年生存率最高，在大多数其他国家为20% - 60%。在大多数纳入的国家中，鳞状细胞癌和腺癌的年龄标准化5年生存率相似，2010 - 2014年诊断的成年人约为15% - 20%，尽管鳞状细胞癌的国际差异更大。在大多数国家，鳞状细胞癌和腺癌的生存率在2000 - 2004年和2010 - 2014年期间增加了不到5%。在许多国家，食管癌的存活率仍然很低。亚位点和形态亚型的分布在不同国家之间有所不同，但这些差异并不能完全解释食管癌生存的国际差异。
Esophageal cancer survival is poor worldwide, though there is some variation. Differences in the distribution of anatomical sub‐site and morphological sub‐type may help explain international differences in survival for all esophageal cancers combined. We estimated survival by anatomic sub‐site and morphological sub‐type to understand further the impact of topography and morphology on international comparisons of esophageal cancer survival. We estimated age‐standardized one‐year and five‐year net survival among adults (15‐99 years) diagnosed with esophageal cancer in each of 60 participating countries to monitor survival trends by calendar period of diagnosis (2000‐2004, 2005‐2009, 2010‐2014), sub‐site, morphology, and sex. For adults diagnosed during 2010‐2014, tumors in the lower third of the esophagus were the most common, followed by tumors of overlapping sub‐site and sub‐site not otherwise specified. The proportion of squamous cell carcinomas diagnosed during 2010‐2014 was generally higher in Asian countries (50%‐90%), while adenocarcinomas were more common in Europe, North America and Oceania (50%‐60%). From 2000‐2004 to 2010‐2014, the proportion of squamous cell carcinoma generally decreased, and the proportion of adenocarcinoma increased. Over time, there were few improvements in age‐standardized five‐year survival for each sub‐site. Age‐standardized one‐year survival was highest in Japan for both squamous cell carcinoma (67.7%) and adenocarcinoma (69.0%), ranging between 20%‐60% in most other countries. Age‐standardized five‐year survival from squamous cell carcinoma and adenocarcinoma was similar for most countries included, around 15%‐20% for adults diagnosed during 2010‐2014, though international variation was wider for squamous cell carcinoma. In most countries, survival for both squamous cell carcinoma and adenocarcinoma increased by less than 5% between 2000‐2004 and 2010‐2014. Esophageal cancer survival remains poor in many countries. The distributions of sub‐site and morphological sub‐type vary between countries, but these differences do not fully explain international variation in esophageal cancer survival.
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影响因子：
2.4
作者：
Hamashima, Chisato
通讯作者：
Hamashima, Chisato
影响因子：
8.8
作者：
通讯作者：
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影响因子：
24.5
作者：
Morgan, Eileen;Soerjomataram, Isabelle;Arnold, Melina
通讯作者：
Arnold, Melina
影响因子：
2.6
作者：
Gavin, A. T.;Francisci, S.;Anderson, L. A.
通讯作者：
Anderson, L. A.
DOI：
10.1016/s0140-6736(17)33326-3
发表时间：
2018-03-17
期刊：
Lancet (London, England)
影响因子：
--
作者：
Allemani C;Matsuda T;Di Carlo V;Harewood R;Matz M;Nikšić M;Bonaventure A;Valkov M;Johnson CJ;Estève J;Ogunbiyi OJ;Azevedo E Silva G;Chen WQ;Eser S;Engholm G;Stiller CA;Monnereau A;Woods RR;Visser O;Lim GH;Aitken J;Weir HK;Coleman MP;CONCORD Working Group
通讯作者：
CONCORD Working Group