Targeting Resistance to Targeted Therapies: Combating a Resilient Foe.
Targeting Resistance to Targeted Therapies: Combating a Resilient Foe.
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针对靶向治疗的耐药性:对抗有弹性的敌人。
DOI:
10.1158/1078-0432.ccr-18-3178
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发表时间:
2018
期刊:
影响因子:
--
通讯作者:
Govindan,Ramaswamy
中科院分区:
文献类型:
--
作者:
Devarakonda,Siddhartha;Govindan,Ramaswamy
While the advent of third-generation therapies has dramatically changed the treatment paradigm for EGFR-mutated lung cancer, resistance to these agents inevitably emerges. Understanding resistance mechanisms and their genomic underpinnings is crucial for developing innovative strategies that are capable of meaningfully prolonging patient survival.See related article by Le et al., p. 6195
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影响因子:
2.7
作者:
C. Callaway;C. Falcón;G. Grant;D. Maurer;A. Auerbach;Z. Rosenwaks;M. Pollack
通讯作者:
M. Pollack
DOI:
10.1172/jci107069
发表时间:
1972
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
J. Wybran;M. Carr;H. Fudenberg
通讯作者:
H. Fudenberg
影响因子:
3.4
作者:
P. Morgan‐Capner;J. Morris;M. McIllmurray;J. Thomas;D. Crawford;T. Azim
通讯作者:
T. Azim
影响因子:
4.4
作者:
K. Sakamoto;J. Seeley;T. Lindsten;J. Sexton;J. Yetz;M. Ballow;D. Purtilo
通讯作者:
D. Purtilo
影响因子:
3.3
作者:
HENLE, W;HENLE, GE;HORWITZ, CA
通讯作者:
HORWITZ, CA