Onset of paternal and maternal Gpi-1 expression in preimplantation mouse embryos.
Onset of paternal and maternal Gpi-1 expression in preimplantation mouse embryos.
复制标题
植入前小鼠胚胎中父本和母本 Gpi-1 表达的开始。
DOI:
10.1016/0012-1606(85)90477-4
复制
发表时间:
1985
影响因子:
2.7
通讯作者:
Solter,D
中科院分区:
文献类型:
--
作者:
Gilbert,SF;Solter,D
The initial activation of the glucose phosphate isomerase gene,Gpi-1, was studied in mouse embryos produced by transplanting pronuclei between two strains of mice differing in alleles for this enzyme. Protein isozymes encoded by the embryonic cell nuclei were first detected on Day 4 of embryogenesis, and the maternal and paternal genes are seen to be activated simultaneously. Comparison of isozymes produced by these nuclear-transfer embryos and by F1embryos from these two strains suggests the absence of oocyte mRNA for GPI-1 at the time when these genes are first activated. Thus, the GPI-1 present is derived from newly transcribed mRNA contributed by both maternal and paternal genes. The relative proportion of maternal cytoplasmic GPI-1 enzyme declines from Day 3 to Day 6, such that on Day 6, almost no oocyte GPI-1 is detected.
登录
查看更多内容
DOI:
10.1111/j.1432-0436.1982.tb01276.x
发表时间:
1982
期刊:
Differentiation; research in biological diversity
影响因子:
--
作者:
W. Krietsch;R. Fundele;G. Kuntz;M. Fehlau;K. Bürki;K. Illmensee
通讯作者:
K. Illmensee
DOI:
--
发表时间:
1981
期刊:
影响因子:
--
作者:
V. Papaioannou;J. West;T. Bücher;I. Linke
通讯作者:
I. Linke
影响因子:
2.7
作者:
V. Chapman;W. Whitten;F. Ruddle
通讯作者:
F. Ruddle
影响因子:
56.9
作者:
MCGRATH, J;SOLTER, D
通讯作者:
SOLTER, D