Perinatal Outcomes of Asynchronous Influenza Vaccination, Ceará, Brazil, 2013-2018.
Perinatal Outcomes of Asynchronous Influenza Vaccination, Ceará, Brazil, 2013-2018.
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DOI：
10.3201/eid2709.203791
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发表时间：
2021
影响因子：
11.8
通讯作者：
Lima AAM
中科院分区：
文献类型：
--
作者：
Filho JQ;Junior FS;Lima TBR;Viana VAF;Burgoa JSV;Soares AM;Leite ÁM;Herron SA;Newland HL;Sarnaik KS;Hanson GF;Papin JA;Moore SR;Lima AAM
在巴西的塞阿拉，季节性流感传播在国家年度疫苗接种运动开始之前就开始了。为了评估这种不一致的围产期后果，我们跟踪了2013-2018年期间的严重急性呼吸道感染（SARI），流感和流感免疫接种。在3，297例SARI病例中，145例（4.4%）发生在孕妇中。全州疫苗接种覆盖率>80%;然而，全国疫苗接种运动在流感高峰期期间或之后开始。流感高峰期后30 ~ 40周，出生体重下降40 g，早产率从10.7%上升到15.5%。我们确定了61名在怀孕期间患有SARI的母亲所生的孩子;他们出生时体重比122名新生儿对照组轻10%，更有可能早产。在塞阿拉州，流感疫苗接种运动的时机不当对围产期结局产生不利影响。由于塞阿拉是巴西从北到南季节性流感传播的假定起点，因此，尽早开展全国免疫接种活动将为塞阿拉及其他地区的孕妇及其胎儿提供更大的保护。
In Ceará, Brazil, seasonal influenza transmission begins before national annual vaccination campaigns commence. To assess the perinatal consequences of this misalignment, we tracked severe acute respiratory infection (SARI), influenza, and influenza immunizations during 2013–2018. Among 3,297 SARI cases, 145 (4.4%) occurred in pregnant women. Statewide vaccination coverage was >80%; however, national vaccination campaigns began during or after peak influenza season. Thirty to forty weeks after peak influenza season, birthweights decreased by 40 g, and rates of prematurity increased from 10.7% to 15.5%. We identified 61 children born to mothers with SARI during pregnancy; they weighed 10% less at birth and were more likely to be premature than 122 newborn controls. Mistiming of influenza vaccination campaigns adversely effects perinatal outcomes in Ceará. Because Ceará is the presumptive starting point for north-to-south seasonal influenza transmission in Brazil, earlier national immunization campaigns would provide greater protection for pregnant women and their fetuses in Ceará and beyond.
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影响因子：
168.9
作者：
Victora, Cesar G.;Adair, Linda;Fall, Caroline;Hallal, Pedro C.;Martorell, Reynaldo;Richter, Linda;Sachdev, Harshpal Singh
通讯作者：
Sachdev, Harshpal Singh
影响因子：
3.7
作者：
Almeida, Alexandra;Codeco, Claudia;Luz, Paula
通讯作者：
Luz, Paula
DOI：
10.4269/ajtmh.2009.81.180
发表时间：
2009-07-01
影响因子：
3.3
作者：
Moura, Fernanda E. A.;Perdigao, Anne C. B.;Siqueira, Marilda M.
通讯作者：
Siqueira, Marilda M.
影响因子：
3.9
作者：
Schlaudecker EP;Steinhoff MC;Moore SR
通讯作者：
Moore SR
DOI：
10.4269/ajtmh.2002.66.590
发表时间：
2002-05-01
影响因子：
3.3
作者：
Niehaus, MD;Moore, SR;Guerrant, RL
通讯作者：
Guerrant, RL