Risk factors for hearing impairment among U.S. adults with diabetes: National Health and Nutrition Examination Survey 1999-2004.
Risk factors for hearing impairment among U.S. adults with diabetes: National Health and Nutrition Examination Survey 1999-2004.
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DOI：
10.2337/dc10-2161
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发表时间：
2011-07
期刊：
影响因子：
16.2
通讯作者：
Cowie CC
中科院分区：
文献类型：
--
作者：
Bainbridge KE;Hoffman HJ;Cowie CC
本研究的目的是在全国具有代表性的糖尿病成年人样本中检查低/中频和高频听力损伤的危险因素。数据来自536名参与者，年龄在20-69岁之间，患有诊断或未诊断的糖尿病，他们在1999-2004年期间完成了全国健康和营养检查调查（NHANES）的听力测试。我们将听力障碍定义为在低/中频（500; 1，000;和2，000 Hz）和高频（3，000; 4，000; 6，000;和8，000 Hz）下纯音听阈的纯音平均听力水平>25 dB，并使用逻辑回归确定独立的风险因素。控制年龄、种族和婚姻状况，HDL <40 mg/dL与低/中频听力损伤相关的优势比为2.20（95% CI 1.28-3.79），健康状况不佳为3.55（1.57-8.03）。控制年龄、种族/民族、性别和收入/贫困比，冠心病史与高频听力损伤相关的优势比为4.39（1.26-15.26），周围神经病变为4.42（1.26-15.45）。低HDL、冠心病、周围神经病变和健康状况不佳是糖尿病患者听力受损的潜在可预防相关因素。血糖控制、诊断后的年数和血糖药物的类型与听力损害无关。
The objective of this study was to examine the risk factors of low/mid-frequency and high-frequency hearing impairment among a nationally representative sample of diabetic adults. Data came from 536 participants, aged 20–69 years, with diagnosed or undiagnosed diabetes who completed audiometric testing during 1999–2004 in the National Health and Nutrition Examination Survey (NHANES). We defined hearing impairment as the pure-tone average >25 dB hearing level of pure-tone thresholds at low/mid-frequencies (500; 1,000; and 2,000 Hz) and high frequencies (3,000; 4,000; 6,000; and 8,000 Hz) and identified independent risk factors using logistic regression. Controlling for age, race/ethnicity, and marital status, odds ratios for associations with low/mid-frequency hearing impairment were 2.20 (95% CI 1.28–3.79) for HDL <40 mg/dL and 3.55 (1.57–8.03) for poor health. Controlling for age, race/ethnicity, sex, and income-to-poverty ratio, odds ratios for associations with high-frequency hearing impairment were 4.39 (1.26–15.26) for history of coronary heart disease and 4.42 (1.26–15.45) for peripheral neuropathy. Low HDL, coronary heart disease, peripheral neuropathy, and having poor health are potentially preventable correlates of hearing impairment for people with diabetes. Glycemic control, years since diagnosis, and type of glycemic medication were not associated with hearing impairment.
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影响因子：
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作者：
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