Comorbidity profiles and inpatient outcomes during hospitalization for heart failure: an analysis of the U.S. Nationwide inpatient sample.
Comorbidity profiles and inpatient outcomes during hospitalization for heart failure: an analysis of the U.S. Nationwide inpatient sample.
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DOI：
10.1186/1471-2261-14-73
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发表时间：
2014-06-05
影响因子：
2.1
通讯作者：
Mudd JO
中科院分区：
文献类型：
--
作者：
Lee CS;Chien CV;Bidwell JT;Gelow JM;Denfeld QE;Masterson Creber R;Buck HG;Mudd JO
心力衰竭(HF)的治疗在存在合并症时尤其复杂。我们试图找出心力衰竭住院期间共病特征与住院结果之间的关系。潜伏混合物模型被用来从2009年全国住院样本(n = 192,327)中确定成人住院期间因心力衰竭而合并疾病的常见情况。大多数患者的出院表现为“常见”并存。“生活方式”的特征是无并发症的糖尿病、高血压、慢性肺病和肥胖症的高患病率。具有“肾脏”特征的患者中，肾脏疾病、并发糖尿病以及液体和电解质失衡的患病率最高。“神经血管”特征代表脑血管疾病、瘫痪、心肌梗死和外周血管疾病的最高患病率。与普通资料相比，生活方式资料与住院时间(LOS)延长15%和费用增加12%相关，肾脏资料与死亡风险增加30%，LOS增加27%，费用增加24%，神经血管情况与死亡风险增加45%，LOS增加34%，费用增加37%(均为p <； 0.001)。共病特征有助于识别死亡风险更高、住院时间更长以及在因心力衰竭住院期间积累更多费用的成年人。
Treatment of heart failure (HF) is particularly complex in the presence of comorbidities. We sought to identify and associate comorbidity profiles with inpatient outcomes during HF hospitalizations. Latent mixture modeling was used to identify common profiles of comorbidities during adult hospitalizations for HF from the 2009 Nationwide Inpatient Sample (n = 192,327). Most discharges were characterized by "common" comorbidities. A "lifestyle" profile was characterized by a high prevalence of uncomplicated diabetes, hypertension, chronic pulmonary disorders and obesity. A "renal" profile had the highest prevalence of renal disease, complicated diabetes, and fluid and electrolyte imbalances. A "neurovascular" profile represented the highest prevalence of cerebrovascular disease, paralysis, myocardial infarction and peripheral vascular disease. Relative to the common profile, the lifestyle profile was associated with a 15% longer length of stay (LOS) and 12% greater cost, the renal profile was associated with a 30% higher risk of death, 27% longer LOS and 24% greater cost, and the neurovascular profile was associated with a 45% higher risk of death, 34% longer LOS and 37% greater cost (all p < 0.001). Comorbidity profiles are helpful in identifying adults at higher risk of death, longer length of stay, and accumulating greater costs during hospitalizations for HF.
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影响因子：
7.2
作者：
DEYO, RA;CHERKIN, DC;CIOL, MA
通讯作者：
CIOL, MA
影响因子：
3
作者：
Elixhauser, A;Steiner, C;Coffey, RN
通讯作者：
Coffey, RN
DOI：
10.1111/j.1751-9004.2007.00054.x
发表时间：
2008-01-01
影响因子：
4.6
作者：
Jung, Tony;Wickrama, K. A. S.
通讯作者：
Wickrama, K. A. S.
影响因子：
4.6
作者：
Murad, Khalil;Kitzman, Dalane W.
通讯作者：
Kitzman, Dalane W.
DOI：
10.1513/pats.200701-001fm
发表时间：
2007-10-01
期刊：
Proceedings of the American Thoracic Society
影响因子：
--
作者：
Mannino, David M;Braman, Sidney
通讯作者：
Braman, Sidney