Serum antibody responses to Streptococcus mutans antigens in humans systemically infected with oral streptococci.
Serum antibody responses to Streptococcus mutans antigens in humans systemically infected with oral streptococci.
复制标题
全身感染口腔链球菌的人体对变形链球菌抗原的血清抗体反应。
DOI:
10.1111/j.1399-302x.1992.tb00630.x
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发表时间:
1992
影响因子:
--
通讯作者:
Henrichsen,J
中科院分区:
文献类型:
--
作者:
Russell,MW;Wu,HY;White,PL;Kilian,M;Henrichsen,J
Sera from patients with subacute bacterial endocarditis (SBE) due toStreptococcus mutansor other oral streptococci and from normal subjects were assayed by enzyme‐linked immunosorbent assay for antibodies to definedS. mutansantigens. Antibodies of IgG and IgA isotypes to Ag I/II and Ag III were greatly elevated inS. mutans‐SBE sera, and the IgA antibodies in 3 sera included both polymeric and monomeric forms. Elevated IgM and IgG anti‐lipoteichoic acid and IgG and IgA anti‐serotype c polysaccharide antibodies were also found. The sera of 4 of 6 patients infected with other oral streptococci also displayed antibodies toS. mutansAg I/II. Sera of 3 patients infected withStreptococcus mitis or Streptococcus orallis.but none of thes. mutans‐infected cases, showed elevated antibodies to human heart sarcolemma, and all SBE sera had elevated rheumatoid factor. These results suggest that the known surface protein antigens ofS. mutansare immunodominant in humans, and are not likely to be heart cross‐reactive.
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影响因子:
3.1
作者:
T. Lehner;M. Russell;J. Caldwell;R. Smith
通讯作者:
R. Smith
DOI:
--
发表时间:
1988
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Swartzwelder,FJ;Barua,PK;Albini,B;Stinson,MW
通讯作者:
Stinson,MW
影响因子:
3.2
作者:
A. J. Wicken;J. Gibbens;K. Knox
通讯作者:
K. Knox
影响因子:
15.3
作者:
I. V. D. Rijn;JB Sabriskie;M. Mccarty
通讯作者:
M. Mccarty
影响因子:
4.8
作者:
B. Maisch;H. Eichstädt;K. Kochsiek
通讯作者:
K. Kochsiek