Histamine as an emergent indoor contaminant: Accumulation and persistence in bed bug infested homes.
Histamine as an emergent indoor contaminant: Accumulation and persistence in bed bug infested homes.
复制标题
DOI：
10.1371/journal.pone.0192462
复制
发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Schal C
中科院分区：
文献类型：
--
作者：
DeVries ZC;Santangelo RG;Barbarin AM;Schal C
组胺用于支气管和皮肤激发，但很少被认为是过敏性疾病的环境危险因素。由于臭虫排泄出大量组胺作为其聚集信息素的组成部分，因此我们试图确定组胺是否在臭虫出没的房屋中积聚在家庭灰尘中，以及通过空间加热消灭臭虫对灰尘中组胺水平的影响。我们在消灭臭虫之前和之后三个月内收集了家中的灰尘并分析了组胺。臭虫出没的家庭中的组胺水平非常高（平均值 = 54.6±18.9 μg/100 mg 筛分的家庭灰尘），并且显着高于未感染臭虫的对照家庭（平均 < 2.5±1.9 μg/100 mg 筛分的家庭灰尘）。即使在治疗后三个月，消除臭虫感染的热处理也未能降低组胺水平。我们报告了家庭灰尘中的组胺水平与臭虫感染之间存在明显的关联。高浓度、持久性以及在睡眠期间与人类的接近表明，臭虫产生的组胺可能是一种新出现的污染物，并对室内环境造成严重的健康风险。
Histamine is used in bronchial and dermal provocation, but it is rarely considered an environmental risk factor in allergic disease. Because bed bugs defecate large amounts of histamine as a component of their aggregation pheromone, we sought to determine if histamine accumulates in household dust in bed bug infested homes, and the effects of bed bug eradication with spatial heat on histamine levels in dust. We collected dust in homes and analyzed for histamine before, and up to three months after bed bug eradication. Histamine levels in bed bug infested homes were remarkably high (mean = 54.6±18.9 μg/100 mg of sieved household dust) and significantly higher than in control homes not infested with bed bugs (mean < 2.5±1.9 μg/100 mg of sieved household dust). Heat treatments that eradicated the bed bug infestations failed to reduce histamine levels, even three months after treatment. We report a clear association between histamine levels in household dust and bed bug infestations. The high concentrations, persistence, and proximity to humans during sleep suggest that bed bug-produced histamine may represent an emergent contaminant and pose a serious health risk in the indoor environment.
登录
查看更多内容
影响因子：
14.2
作者：
Arbes, SJ;Sever, M;Zeldin, DC
通讯作者：
Zeldin, DC
影响因子：
12.4
作者：
Gschwandtner M;Mildner M;Mlitz V;Gruber F;Eckhart L;Werfel T;Gutzmer R;Elias PM;Tschachler E
通讯作者：
Tschachler E
影响因子：
14.2
作者：
deBlay, F;Sanchez, J;Pauli, G
通讯作者：
Pauli, G
DOI：
10.1080/15428119891010668
发表时间：
1998-06-01
期刊：
AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL
影响因子：
--
作者：
Kullman, GJ;Thorne, PS;Merchant, JA
通讯作者：
Merchant, JA
影响因子：
3.8
作者：
Leulmi, Hamza;Bitam, Idir;Parola, Philippe
通讯作者：
Parola, Philippe