Opioid overdose decedent characteristics during COVID-19.
Opioid overdose decedent characteristics during COVID-19.
复制标题
DOI：
10.1080/07853890.2022.2067350
复制
发表时间：
2022-12
影响因子：
4.4
通讯作者：
Jalali, Mohammad S.
中科院分区：
文献类型：
--
作者：
Garcia, Gian-Gabriel P.;Stringfellow, Erin J.;DiGennaro, Catherine;Poellinger, Nicole;Wood, Jaden;Wakeman, Sarah;Jalali, Mohammad S.
随着COVID-19在美国的出现，几份报告强调了初步数据中阿片类药物过量的比例增加。然而，很少有人知道州一级阿片类药物过量死亡趋势和死者特征是如何使用官方死亡记录演变的。我们要求所有50个州和哥伦比亚特区提供2018-2020年的生命统计数据，并从14个州获得数据。考虑到COVID-19，我们排除了2020年3月以后没有数据的州，留下11个州进行分析。我们定义了从3月13日到每个州数据中最新可靠日期的特定州分析期，然后进行回顾性逐年分析，比较阿片类药物相关过量死亡率，特定阿片类药物和其他精神活性物质的存在，以及死者的性别，种族和年龄从2020年到2019年和2019年到2018年每个州的分析期。我们使用联合点回归评估了2020年与2019年相比阿片类药物过量死亡的显著变化是新的还是持续的趋势。我们发现阿拉斯加（55.3%）、科罗拉多（80.2%）、印第安纳州（40.1%）、内华达州（50.0%）、北卡罗来纳州（30.5%）、罗得岛（29.6%）和弗吉尼亚州（66.4%）的阿片类药物相关过量死亡率显著增加--所有这些都延续了之前的趋势。阿拉斯加（136.5%）、印第安纳州（27.6%）和弗吉尼亚州（16.5%）的合成阿片类药物过量死亡人数增加是新的，而科罗拉多（44.4%）、康涅狄格州（3.6%）、内华达州（75.0%）和北卡罗来纳州（14.6%）的情况仍在继续。我们发现印第安纳州的男性死亡人数有新的增加（12.0%），科罗拉多的男性死亡人数继续增加（15.2%）。我们还发现，在马萨诸塞州（43.9%）和弗吉尼亚州（33.7%），非西班牙裔黑人死者的数量持续增加。我们的研究结果强调了COVID-19大流行期间阿片类药物过量趋势的变化，这些变化无法从疾病控制和预防中心发布的汇总或临时阿片类药物过量死亡数据中提取。芬太尼和其他合成阿片类药物继续推动致命过量的增加，因此很难将这些趋势与任何可能的COVID-19相关因素分开。在一些州，非西班牙裔黑人在阿片类药物过量死亡中所占的比例越来越大。各国在人口动态统计数据报告方面的局限性和差异使得获取和分析类阿片相关过量死亡的最新数据具有挑战性。该研究分析了来自11个州的重要统计数据，突出了其中10个州阿片类药物过量死亡和死者特征的新趋势。这些发现可以为各州的公共卫生干预措施提供信息，并强调需要及时和全面的致命阿片类药物过量数据，特别是在COVID-19等并发危机中。
Alongside the emergence of COVID-19 in the United States, several reports highlighted increasing rates of opioid overdose from preliminary data. Yet, little is known about how state-level opioid overdose death trends and decedent characteristics have evolved using official death records. We requested vital statistics data from 2018–2020 from all 50 states and the District of Columbia, receiving data from 14 states. Accounting for COVID-19, we excluded states without data past March 2020, leaving 11 states for analysis. We defined state-specific analysis periods from March 13 until the latest reliable date in each state’s data, then conducted retrospective year-over-year analyses comparing opioid-related overdose death rates, the presence of specific opioids and other psychoactive substances, and decedents’ sex, race, and age from 2020 to 2019 and 2019 to 2018 within each state’s analysis period. We assessed whether significant changes in 2020 vs. 2019 in opioid overdose deaths were new or continuing trends using joinpoint regression. We found significant increases in opioid-related overdose death rates in Alaska (55.3%), Colorado (80.2%), Indiana (40.1%), Nevada (50.0%), North Carolina (30.5%), Rhode Island (29.6%), and Virginia (66.4%) – all continuing previous trends. Increases in synthetic opioid-involved overdose deaths were new in Alaska (136.5%), Indiana (27.6%), and Virginia (16.5%), whilst continuing in Colorado (44.4%), Connecticut (3.6%), Nevada (75.0%), and North Carolina (14.6%). We found new increases in male decedents in Indiana (12.0%), and continuing increases in Colorado (15.2%). We also found continuing increases in Black non-Hispanic decedents in Massachusetts (43.9%) and Virginia (33.7%). Our results highlight shifts in opioid overdose trends during the COVID-19 pandemic that cannot otherwise be extracted from aggregated or provisional opioid overdose death data such as those published by the Centres for Disease Control and Prevention. Fentanyl and other synthetic opioids continue to drive increases in fatal overdoses, making it difficult to separate these trends from any possible COVID-19-related factors. Black non-Hispanic people are making up an increasing proportion of opioid overdose deaths in some states. State-specific limitations and variations in data-reporting for vital statistics make it challenging to acquire and analyse up-to-date data on opioid-related overdose deaths. More timely and comprehensive data are needed to generate broader insights on the nature of the intersecting opioid and COVID-19 crises This research analyzes vital statistics data from 11 states, highlighting new trends in opioid overdose deaths and decedent characteristics across 10 of these states. These findings can inform state-specific public health interventions and highlight the need for timely and comprehensive fatal opioid overdose data, especially amidst concurrent crises such as COVID-19.
登录
查看更多内容
影响因子：
20.8
作者：
Cerdá M;Krawczyk N;Hamilton L;Rudolph KE;Friedman SR;Keyes KM
通讯作者：
Keyes KM
影响因子：
4.2
作者：
Root ED;Slavova S;LaRochelle M;Feaster DJ;Villani J;Defiore-Hyrmer J;El-Bassel N;Ergas R;Gelberg K;Jackson R;Manchester K;Parikh M;Rock P;Walsh SL
通讯作者：
Walsh SL
影响因子：
4.2
作者：
Kelley MA;Lucas J;Stewart E;Goldman D;Doctor JN
通讯作者：
Doctor JN
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
2.2
作者：
Beasley, TM;Schumacker, RE
通讯作者：
Schumacker, RE