Environmental chemical exposures among Greenlandic children in relation to diet and residence.
Environmental chemical exposures among Greenlandic children in relation to diet and residence.
复制标题
格陵兰儿童与饮食和居住有关的环境化学物质暴露。
DOI:
10.1080/22423982.2019.1642090
复制
发表时间:
2019
影响因子:
1.3
通讯作者:
Grandjean,Philippe
中科院分区:
文献类型:
--
作者:
Timmermann,ClaraAmalieGade;Pedersen,HenningSloth;Budtz-Jørgensen,Esben;Bjerregaard,Peter;Oulhote,Youssef;Weihe,Pál;Nielsen,Flemming;Grandjean,Philippe
The objective of this study was to identify geographic, dietary, and other predictors for childhood exposure to perfluoroalkyl substances (PFASs), polychlorinated biphenyls (PCBs), and methylmercury in Greenlandic children. The study includes cross-sectional data from 367 Greenlandic children aged 7 to 12 years examined during 2012–2015.A parent or guardian participated in a structured interview, and a blood sample from the child was analysed for PFASs, PCBs and total mercury. Predictors for the environmental exposures were identified using linear regression. Area of residence was found to have the strongest explanatory power, accounting for 24% to 68% of the variance in the serum concentrations. Information about diet was available for two-thirds of the children, and among these, consumption of traditional Greenlandic food accounted for 2% to 10% of the variance in the biomarker concentrations. Models including all predictors associated with at least one of the environmental chemicals explained 19% to 54% of the total variance. In conclusion, area is a likely proxy for a traditional marine diet, and together area and diet constitute the most important predictors of exposure to methylmercury, PCBs and PFASs among Greenlandic children.
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DOI:
--
发表时间:
1983
期刊:
Journal of Laboratory and Clinical Medicine
影响因子:
--
作者:
E. Abraham;R. E. Perry;M. Stallings
通讯作者:
M. Stallings
影响因子:
7.7
作者:
G. Segre;G. Turco;G. Vercellone
通讯作者:
G. Vercellone
影响因子:
15.9
作者:
BAGDADE, JD;BIERMAN, EL;PORTE, D
通讯作者:
PORTE, D
影响因子:
15.9
作者:
POLONSKY, KS;GIVEN, BD;VANCAUTER, E
通讯作者:
VANCAUTER, E
影响因子:
--
作者:
M. Ookhtens;D. Marsh;S. W. Smith;R. Bergman;F. Yates
通讯作者:
F. Yates