Curation of complex, context-dependent immunological data.

Curation of complex, context-dependent immunological data.
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DOI:
10.1186/1471-2105-7-341
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发表时间:
2006-07-12
期刊:
影响因子:
3
通讯作者:
Sette A
Sette A
中科院分区:
生物学4区
文献类型:
--
作者:
Vita R;Vaughan K;Zarebski L;Salimi N;Fleri W;Grey H;Sathiamurthy M;Mokili J;Bui HH;Bourne PE;Ponomarenko J;de Castro R Jr;Chan RK;Sidney J;Wilson SS;Stewart S;Way S;Peters B;Sette A

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免疫表位数据库和分析资源(IEDB)致力于捕获,存储和分析复杂的免疫表位相关数据。为了以有效和准确的方式从科学文献中识别和提取相关数据,开发了用于手动和半自动注释的新过程。正式的策展战略使大量与背景相关的数据得以处理,这些数据现在以可访问和透明的格式提供给科学界。本文描述的经验适用于容纳复杂生物数据并需要高水平的策展专业知识的其他数据库。
The Immune Epitope Database and Analysis Resource (IEDB) is dedicated to capturing, housing and analyzing complex immune epitope related data . To identify and extract relevant data from the scientific literature in an efficient and accurate manner, novel processes were developed for manual and semi-automated annotation. Formalized curation strategies enable the processing of a large volume of context-dependent data, which are now available to the scientific community in an accessible and transparent format. The experiences described herein are applicable to other databases housing complex biological data and requiring a high level of curation expertise.
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