Effect of physical activity and exercise on endometriosis-associated symptoms: a systematic review.
Effect of physical activity and exercise on endometriosis-associated symptoms: a systematic review.
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DOI：
10.1186/s12905-021-01500-4
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发表时间：
2021-10-09
期刊：
影响因子：
--
通讯作者：
Tellum T
中科院分区：
文献类型：
--
作者：
Tennfjord MK;Gabrielsen R;Tellum T
子宫内膜异位症是一种常见的良性妇科疾病，有可能因疼痛和生活质量下降而衰弱。激素和手术等治疗方式有局限性，不能治疗子宫内膜异位症引起的所有问题，体育活动（PA）和运动被建议作为替代治疗方法。本研究的目的是进行系统回顾和荟萃分析，以评估PA和运动对子宫内膜异位症相关症状的影响。系统地检索了11个数据库。研究选择、质量评估和数据提取由两名独立研究人员按照PRISMA指南进行。入选标准是诊断为子宫内膜异位症的妇女接受干预（PA和/或锻炼）。主要结果为疼痛强度，但所有结果均被接受。本研究筛选了1045篇引文的合格性。确定了四项干预性研究，其中一项存在致命的设计缺陷，因此被排除。3项研究，2项随机对照试验（RCT）和1项无对照组的前后研究，涉及109例患者纳入描述性综合。干预措施包括柔韧性和力量训练、心血管健康和瑜伽，每周进行1至4次，总持续时间为8-24周，有或无监督。只有一项研究发现疼痛强度有所改善。一项研究表明压力水平会降低。由于研究结果和测量方法的异质性以及混杂因素，无法进行定量荟萃分析。由于纳入研究的显著局限性，PA和运动作为治疗子宫内膜异位症相关症状的效果无法确定。未来的研究应以高方法学质量的随机对照试验为基础，测量和报告相关的核心结果，如疼痛、症状和生活质量的改善，以及患者的可接受性和满意度。此外，这些结果需要使用可靠和有效的工具来衡量。CRD42021233138。在线版本包含补充材料，可在10.1186/s12905-021-01500-4获得。
Endometriosis is a common benign gynecological disease that has the potential to debilitate due to pain and reduced quality of life. Treatment modalities such as hormones and surgery have limitations and do not treat all dimensions of the problems caused by endometriosis, and physical activity (PA) and exercise have been suggested as alternative treatments. Aim of this study was to perform a systematic review and meta-analysis to assess the effect of PA and exercise on endometriosis-associated symptoms. Eleven databases were searched systematically. Study selection, quality assessment, and data extraction were carried out by two independent researchers in accordance with PRISMA guidelines. Eligibility criteria were women with diagnosed endometriosis receiving an intervention (PA and/or exercise). The primary outcome was pain intensity, but all outcomes were accepted. This study screened 1045 citations for eligibility. Four interventional studies were identified, of which one showed fatal design flaws and so was excluded. Three studies, two randomized controlled trials (RCT) and one pre-post study with no control group, involving 109 patients were included in a descriptive synthesis. The interventions included flexibility and strength training, cardiovascular fitness, and yoga, and were performed from one to four times per week for a total duration of 8–24 weeks, with or without supervision. Only one study found improvements in pain intensity. One study showed decreases in stress levels. Due to the heterogeneity of the study outcomes and measures, as well as confounding factors, a quantitative meta-analysis could not be performed. The effect of PA and exercise as treatments for endometrioses-associated symptoms could not be determined due to significant limitations of the included studies. Future research should be based on RCTs of high methodological quality, measuring and reporting relevant core outcomes such as pain, improvements in symptoms and quality of life, and acceptability and satisfaction from the perspectives of patients. Furthermore, these outcomes need to be measured using reliable and validated tools. CRD42021233138. The online version contains supplementary material available at 10.1186/s12905-021-01500-4.
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影响因子：
15.8
作者：
Moher D;Liberati A;Tetzlaff J;Altman DG;PRISMA Group
通讯作者：
PRISMA Group
DOI：
10.1007/s12160-016-9844-2
发表时间：
2017-04
期刊：
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
影响因子：
--
作者：
Hilton L;Hempel S;Ewing BA;Apaydin E;Xenakis L;Newberry S;Colaiaco B;Maher AR;Shanman RM;Sorbero ME;Maglione MA
通讯作者：
Maglione MA
影响因子：
8.3
作者：
Alio, L.;Angioni, S.;Zupi, E.
通讯作者：
Zupi, E.
DOI：
10.1016/0020-7292(95)02359-k
发表时间：
1995-06-01
影响因子：
3.8
作者：
CARPENTER, SE;TJADEN, B;KIMBALL, A
通讯作者：
KIMBALL, A
影响因子：
--
作者：
Awad, Eman;Ahmed, Hamada Ahmed Hamada;Abbas, Rami
通讯作者：
Abbas, Rami