Insight into vital role of autophagy in sustaining biological control potential of fungal pathogens against pest insects and nematodes.

Insight into vital role of autophagy in sustaining biological control potential of fungal pathogens against pest insects and nematodes.
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深入了解自噬在维持真菌病原体对害虫和线虫的生物控制潜力中的重要作用

DOI:
10.1080/21505594.2018.1518089
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发表时间:
2019-12
期刊:
影响因子:
5.2
通讯作者:
Feng MG
Feng MG
中科院分区:
生物学2区
文献类型:
--
作者:
Ying SH;Feng MG

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ABSTRACT Autophagy is a conserved self-degradation mechanism that governs a large array of cellular processes in filamentous fungi. Filamentous insect and nematode mycopthogens function in the natural control of host populations and have been widely applied for biological control of insect and nematode pests. Entomopathogenic and nematophagous fungi have conserved “core” autophagy machineries that are analogous to those found in yeast but also feature several proteins involved in specific aspects of the autophagic pathways. Here, we review the functions of autophagy in protecting fungal cells from starvation and stress cues and sustaining cell differentiation, asexual development and virulence. An emphasis is placed upon the regulatory mechanisms involved in autophagic and non-autophagic roles of some autophagy-related genes. Methods used for monitoring conserved or specific autophagic events in fungal pathogens are also discussed.
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