Manufacturing polymeric porous capsules.

Manufacturing polymeric porous capsules.
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DOI:
10.1039/d1cc06565c
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发表时间:
2022-04-05
期刊:
Chemical communications (Cambridge, England)
影响因子:
--
通讯作者:
Elani Y
Elani Y
中科院分区:
其他
文献类型:
--
作者:
Contini C;Hu W;Elani Y

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聚合物多孔胶囊代表着非常有前途的系统,允许与周围环境进行大小选择的透壳材料交换。它们在药物输送和化学微反应器、人工细胞科学和合成生物学等领域具有巨大的应用潜力。由于其多孔的核壳结构,聚合物多孔胶囊具有更高的渗透性,能够在交换小分子的同时保留较大的化合物和大分子。材料的跨胶囊转移受其截留孔径的调节,这取决于材料的分子组成和所采用的制备方法。本文概述了制备聚合物多孔胶囊的主要策略,并为设计孔径可控的聚合物胶囊提供了一些实用的指导。本文概述了目前制备聚合物多孔胶囊所采用的最先进的策略,它代表了一种新的超分子结构,拓宽了自组装聚合物系统的适用性和通用性。
Polymeric porous capsules represent hugely promising systems that allow a size-selective through-shell material exchange with their surroundings. They have vast potential in applications ranging from drug delivery and chemical microreactors to artificial cell science and synthetic biology. Due to their porous core–shell structure, polymeric porous capsules possess an enhanced permeability that enables the exchange of small molecules while retaining larger compounds and macromolecules. The cross-capsule transfer of material is regulated by their pore size cut-off, which depends on the molecular composition and adopted fabrication method. This review outlines the main strategies for manufacturing polymeric porous capsules and provides some practical guidance for designing polymeric capsules with controlled pore size. The review paper outlines the current state-of-the-art strategies adopted to fabricate polymeric porous capsules which represent a novel supramolecular construct that broadens the applicability and versatility of self-assembled polymeric systems.
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