A Tour of TOR Complex Signaling in Plants.

A Tour of TOR Complex Signaling in Plants.
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DOI:
10.1016/j.tibs.2020.11.004
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发表时间:
2021-05
影响因子:
13.8
通讯作者:
Brandizzi F
Brandizzi F
中科院分区:
生物学1区
文献类型:
--
作者:
Burkart GM;Brandizzi F

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为了确定生长和发育的适当时间,生物体必须感知和处理有关营养物质、能量状态和环境线索的可用性的信息。对于像植物这样的无柄真核生物来说,整合这些信息对于生或死的决定至关重要。近30年来,雷帕霉素(TOR)的保守磷脂酰肌醇3-激酶相关蛋白激酶(PIKKs)靶标已被确立为整合外部和内部代谢线索的中心枢纽。尽管在真核生物中功能保守,TOR复合物在植物中已经进化出特定的功能和机制特征。在这里,我们提出了最近的研究结果,植物TOR复合物,强调保守和独特的性质,这一关键的生长调节剂及其在植物生命的多个方面的作用。
In order to identify the appropriate times for growth and development, organisms must sense and process information about the availability of nutrients, energy status, and environmental cues. For sessile eukaryotes like plants, integrating such information can be critical in life or death decisions. For nearly 30 years, the conserved phosphatidylinositol 3-kinase-related protein kinases (PIKKs) target of rapamycin (TOR) has been established as a central hub for integrating external and internal metabolic cues. Despite the functional conservation across eukaryotes, the TOR complex has evolved specific functional and mechanistic features in plants. Here we present recent findings on the plant TOR complex that highlight conserved and unique nature of this critical growth regulator and its role in multiple aspects of plant life.
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