Are diet quality scores after breast cancer diagnosis associated with improved breast cancer survival?

Are diet quality scores after breast cancer diagnosis associated with improved breast cancer survival?
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DOI:
10.1080/01635581.2013.804939
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发表时间:
2013
期刊:
Nutrition and cancer
影响因子:
--
通讯作者:
Holmes MD
Holmes MD
中科院分区:
其他
文献类型:
--
作者:
Izano MA;Fung TT;Chiuve SS;Hu FB;Holmes MD

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以前的研究发现,富含水果和蔬菜的饮食与降低乳腺癌死亡率有关。然而,这些饮食模式并不一定反映整体饮食质量。尚未评估乳腺癌死亡率与先验定义的饮食评分之间的关联,这些评分基于推荐的饮食指南并反映饮食质量。我们假设基于推荐指南的饮食质量指数与乳腺癌幸存者乳腺癌和非乳腺癌死亡率风险降低相关。我们检查了饮食方法停止高血压(DASH)评分和替代健康饮食指数(AHEI)-2010之间的关系,以及来自护士健康研究的乳腺癌患者的乳腺癌死亡率和总死亡率。坚持DASH风格和AHEI-2010饮食与非乳腺癌死亡率风险降低相关(比较第五个五分位数与第一个五分位数,DASH的RR = 0.72,95%CI:0.53-0.99,p趋势= 0.03,AHEI-2010的RR = 0.57,95%CI:0.42-0.77,p趋势<0.0001)。饮食评分与乳腺癌死亡率无显著相关性。我们的研究结果表明,在乳腺癌诊断后坚持更高质量的饮食不会显著改变乳腺癌死亡和复发的风险。然而,乳腺癌后健康的饮食选择与乳腺癌妇女非乳腺癌死亡率的风险降低有关。
Previous studies have found that diets rich in fruits and vegetables are associated with reduced breast cancer mortality. However, these eating patterns do not necessarily reflect overall diet quality. The association of breast cancer mortality with a priori defined dietary scores, which are based on recommended dietary guidelines and reflect diet quality, has not been evaluated. We hypothesized that diet quality indices based on recommended guidelines are associated with decreased risk of breast cancer and non-breast cancer mortality in breast cancer survivors. We examined the association between the Dietary Approaches to Stop Hypertension (DASH) score, and the Alternative Healthy Eating Index (AHEI)-2010, and the risk of breast cancer mortality and total mortality among women from the Nurses’ Health Study diagnosed with breast cancer. Adherence to DASH-style and AHEI-2010 diets were associated with reduced risk of non-breast cancer mortality (comparing the fifth quintile with the first quintile RR = 0.72, 95% CI: 0.53–0.99, p-trend = 0.03 for DASH, and RR = 0.57, 95% CI: 0.42–0.77, p-trend <0.0001 for AHEI-2010). Diet scores were not significantly associated with breast cancer mortality. Our findings suggest that adherence to a higher quality diet after breast cancer diagnosis does not considerably change the risk of breast cancer death and recurrence. However, healthy dietary choices after breast cancer were associated with reduced risk of non-breast cancer mortality in women with breast cancer.
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