The paf gene product modulates asexual development in Penicillium chrysogenum.

The paf gene product modulates asexual development in Penicillium chrysogenum.
复制标题

DOI:
10.1002/jobm.201000321
复制
发表时间:
2011-06
影响因子:
3.1
通讯作者:
Marx, Florentine
Marx, Florentine
中科院分区:
生物学4区
文献类型:
--
作者:
Hegedues, Nikoletta;Sigl, Claudia;Zadra, Ivo;Pocsi, Istvan;Marx, Florentine

文献摘要

参考文献

被引文献

相似文献

产黄青霉分泌一种低分子量、阳离子和富含半胱氨酸的蛋白质(PAF)。它对模式生物构巢曲霉和许多动物园和植物病原真菌具有生长抑制活性,但对生产生物本身仅显示出最小的条件抗真菌活性。在这项研究中,我们提供的证据PAF的一个额外的功能,这是不同的抗真菌活性对假定的生态并发微生物。我们的数据表明PAF通过调节有丝分裂孢子发育的中心调控基因brlA的表达来增强产黄青霉的分生孢子。一个paf缺失菌株表现出显着损害有丝分裂孢子的形成,这支持了我们的假设,PAF在平衡无性分化中起着重要作用。
Penicillium chrysogenum secretes a low molecular weight, cationic and cysteine-rich protein (PAF). It has growth inhibitory activity against the model organism Aspergillus nidulans and numerous zoo- and phytopathogenic fungi but shows only minimal conditional antifungal activity against the producing organism itself. In this study we provide evidence for an additional function of PAF which is distinct from the antifungal activity against putative ecologically concurrent microorganisms. Our data indicate that PAF enhances conidiation in P. chrysogenum by modulating the expression of brlA, the central regulatory gene for mitospore development. A paf deletion strain showed a significant impairment of mitospore formation which sustains our hypothesis that PAF plays an important role in balancing asexual differentiation in P. chrysogenum.
DOI: 10.1111/j.1742-4658.2009.07011.x
发表时间: 2009-05
期刊: The FEBS journal
影响因子: --
作者:
Batta G;Barna T;Gáspári Z;Sándor S;Kövér KE;Binder U;Sarg B;Kaiserer L;Chhillar AK;Eigentler A;Leiter E;Hegedüs N;Pócsi I;Lindner H;Marx F
通讯作者: Marx F
DOI: 10.1016/0378-1119(88)90586-0
发表时间: 1988-01-01
期刊: GENE
影响因子: 3.5
作者:
KOLAR, M;PUNT, PJ;SCHWAB, H
通讯作者: SCHWAB, H
DOI: 10.1038/nbt0587-494
发表时间: 1987-05-01
期刊: BIO-TECHNOLOGY
影响因子: --
作者:
CANTORAL, JM;DIEZ, B;MARTIN, JF
通讯作者: MARTIN, JF
DOI: 10.1007/s00438-001-0609-6
发表时间: 2002-01-01
影响因子: 3.1
作者:
Meyer, V;Wedde, M;Stahl, U
通讯作者: Stahl, U
DOI: 10.1007/s10482-008-9263-x
发表时间: 2008-10-01
影响因子: 2.6
作者:
Galgoczy, Laszlo;Papp, Tamas;Vagvolgyi, Csaba
通讯作者: Vagvolgyi, Csaba