Screening differentially expressed proteins from co-cultured hematopoietic cells and bone marrow-derived stromal cells by quantitative proteomics (SILAC) method

Screening differentially expressed proteins from co-cultured hematopoietic cells and bone marrow-derived stromal cells by quantitative proteomics (SILAC) method
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通过定量蛋白质组学(SILAC)方法筛选共培养的造血细胞和骨髓基质细胞的差异表达蛋白

DOI:
10.1186/s12014-019-9249-x
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发表时间:
2019-07
影响因子:
3.8
通讯作者:
Li Xiang
Li Xiang
中科院分区:
医学2区
文献类型:
--
作者:
Liu Rui;Wang Yi;Li Bingxin;Wang Hui;Guan Feng;Tan Zengqi;Li Xiang

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骨髓基质细胞保护造血细胞,并通过传递大量可变蛋白质来提供耐药性。因此,蛋白质表达的改变通常与细胞间信号转导和细胞功能的调节有关。
Bone marrow stromal cells protect hematopoietic cells and provide drug resistance by delivering bunch of variable proteins. Thus, alterations of protein expression are typically associated with cell–cell signal transduction and regulation of cellular func
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