Following autophagy step by step.
Following autophagy step by step.
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DOI:
10.1186/1741-7007-9-39
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发表时间:
2011-06-02
期刊:
影响因子:
5.4
通讯作者:
Johansen T
中科院分区:
文献类型:
--
作者:
Hansen TE;Johansen T
Autophagy is an evolutionarily conserved lysosomal degradation route for soluble components of the cytosol and organelles. There is great interest in identifying compounds that modulate autophagy because they may have applications in the treatment of major diseases including cancer and neurodegenerative disease. Hundeshagen and colleagues describe this month in BMC Biology a screening assay based on flow cytometry that makes it possible to track distinct steps in the autophagic process and thereby identify novel modulators of autophagy. See research article: http://www.biomedcentral.com/1741-7007/9/38
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