Review: absorption and metabolism of beta-carotene.
Review: absorption and metabolism of beta-carotene.
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回顾:β-胡萝卜素的吸收和代谢。
DOI:
--
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发表时间:
1994
影响因子:
3.5
通讯作者:
X. Wang
中科院分区:
文献类型:
--
作者:
X. Wang
To better understand the potential function of beta-carotene (beta-C) in the prevention of cancer, greater knowledge of beta-C metabolism and a suitable animal model to mimic human beta-C metabolism are necessary. The small intestinal mucosa contains beta-C cleavage enzyme(s), thereby playing an important role in both the provitamin A activity and anti-cancer properties of beta-C. The ability of the ferret (Mustela putorius furo) to absorb intact beta-C makes it an appropriate model for studying human beta-C absorption. This article reviews the absorption and cleavage mechanisms of beta-C in both the human and the ferret. The biosynthesis of retinoic acid (RA) from beta-C via central and eccentric cleavage pathways is reviewed. The possible significance of the conversion of beta-C to RA as an anticancer mechanism is discussed.
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影响因子:
2.9
作者:
Timothy C. Quick;D E Ong
通讯作者:
Timothy C. Quick;D E Ong
影响因子:
--
作者:
Olson,JA
通讯作者:
Olson,JA
DOI:
10.1093/ajcn/53.1.226s
发表时间:
1991
期刊:
The American journal of clinical nutrition
影响因子:
--
作者:
Weisburger,JH
通讯作者:
Weisburger,JH
影响因子:
7.1
作者:
KRINSKY, NI
通讯作者:
KRINSKY, NI
DOI:
10.1016/0005-2760(93)90157-5
发表时间:
1993
期刊:
Biochimica et biophysica acta
影响因子:
--
作者:
Wang,XD;Russell,RM;Marini,RP;Tang,G;Dolnikowski,GG;Fox,JG;Krinsky,NI
通讯作者:
Krinsky,NI