Maternal helminth infections.
Maternal helminth infections.
复制标题
孕产妇蠕虫感染
DOI:
10.1007/978-1-4939-1489-0_2
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发表时间:
2014
影响因子:
--
通讯作者:
Prazeres da Costa C
中科院分区:
文献类型:
--
作者:
Straubinger K;Prazeres da Costa C
Chronic helminth infections are highly prevalent in many parts of the world and a considerable infection rate during pregnancy has been reported. It is becoming clear that the development of the fetal immune system and the immune responses to homologous and possibly even heterologous antigens later in life is already determined in utero. The contributing factors and mechanisms are still under investigation. However, studies have demonstrated that maternal helminth infection can influence susceptibility to a homologous infection during childhood without previous fetomaternal transmission of the infectious agent itself during pregnancy. Whether this is caused e.g. by chronic maternal immune responses (cells or cytokines) such as immuneregulation or transmission of helminth derived antigen/proteins, and furthermore which developmental stage of the offspring’s immune system is affected by such factors e.g. in an epigenetic manner and finally, what clinical implications these results have regarding vaccination strategies, needs to be investigated in the future.
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DOI:
--
发表时间:
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期刊:
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作者:
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通讯作者:
P. Musgrove
DOI:
10.1590/s1020-49892007000900001
发表时间:
2007-10-01
期刊:
Revista Panamericana de Salud Pública
影响因子:
--
作者:
Gotuzzo, Eduardo;Moody, Joel;Vermund, Sten H.
通讯作者:
Vermund, Sten H.