Task modulated brain connectivity of the amygdala: a meta-analysis of psychophysiological interactions.
Task modulated brain connectivity of the amygdala: a meta-analysis of psychophysiological interactions.
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DOI：
10.1007/s00429-016-1239-4
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发表时间：
2017-01
影响因子：
3.1
通讯作者：
Biswal, Bharat B.
中科院分区：
文献类型：
--
作者：
Di, Xin;Huang, Jia;Biswal, Bharat B.
理解杏仁核与其他脑区的功能连接，尤其是任务调节的连接，是理解杏仁核在情绪过程中的作用以及情绪与认知之间相互作用的关键一步。本研究对使用心理生理交互作用（PPI）分析的杏仁核任务调节连接的研究进行了基于坐标的元分析。我们首先使用激活似然估计（ALE）元分析对49项关于不同类型任务的PPI研究进行了分析。广泛的皮质和皮质下区域显示出与杏仁核一致的任务调节连接，包括内侧额叶皮质、双侧脑岛、前扣带回、梭状回、海马旁回、丘脑和基底神经节。这些区域通常与那些显示出与杏仁核共同激活的区域重叠，这表明这些区域和杏仁核不仅一起被激活，而且在任务期间还表现出不同程度的相互作用。对PPI研究子集的进一步分析揭示了受恐惧处理、面部处理和情绪调节调节的与杏仁核的任务特异性功能连接。这些结果表明连接根据任务需求进行动态调节，并为杏仁核在不同情感和认知过程中的功能提供了新的见解。对PPI研究的元分析方法可能为系统研究任务调节连接提供一个框架。
Understanding functional connectivity of the amygdala with other brain regions, especially task modulated connectivity, is a critical step toward understanding the role of the amygdala in emotional processes and the interactions between emotion and cognition. The present study performed coordinate-based meta-analysis on studies of task modulated connectivity of the amygdala which used psychophysiological interaction (PPI) analysis. We first analyzed 49 PPI studies on different types of tasks using activation likelihood estimation (ALE) meta-analysis. Widespread cortical and subcortical regions showed consistent task modulated connectivity with the amygdala, including the medial frontal cortex, bilateral insula, anterior cingulate, fusiform gyrus, parahippocampal gyrus, thalamus, and basal ganglia. These regions were in general overlapped with those showed coactivations with the amygdala, suggesting that these regions and amygdala are not only activated together, but also show different levels of interactions during tasks. Further analyses with subsets of PPI studies revealed task specific functional connectivities with the amygdala that were modulated by fear processing, face processing, and emotion regulation. These results suggest a dynamic modulation of connectivity upon task demands, and provide new insights on the functions of the amygdala in different affective and cognitive processes. The meta-analytic approach on PPI studies may offer a framework toward systematical examinations of task modulated connectivity.
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影响因子：
4.8
作者：
Eickhoff, Simon B.;Laird, Angela R.;Grefkes, Christian;Wang, Ling E.;Zilles, Karl;Fox, Peter T.
通讯作者：
Fox, Peter T.
影响因子：
3.4
作者：
Friedel, Eva;Schlagenhauf, Florian;Heinz, Andreas
通讯作者：
Heinz, Andreas
DOI：
10.1016/j.pnpbp.2013.09.001
发表时间：
2014-01-03
影响因子：
5.6
作者：
Di, Xin;Rypma, Bart;Biswal, Bharat B.
通讯作者：
Biswal, Bharat B.
影响因子：
4.2
作者：
Gorka, Adam X.;Knodt, Annchen R.;Hariri, Ahmad R.
通讯作者：
Hariri, Ahmad R.
DOI：
10.1523/jneurosci.3609-09.2009
发表时间：
2009-11-25
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Blasi G;Lo Bianco L;Taurisano P;Gelao B;Romano R;Fazio L;Papazacharias A;Di Giorgio A;Caforio G;Rampino A;Masellis R;Papp A;Ursini G;Sinibaldi L;Popolizio T;Sadee W;Bertolino A
通讯作者：
Bertolino A