A smartphone-based chip-scale microscope using ambient illumination.

A smartphone-based chip-scale microscope using ambient illumination.
复制标题

DOI:
10.1039/c4lc00523f
复制
发表时间:
2014-08-21
期刊:
影响因子:
6.1
通讯作者:
Yang C
Yang C
中科院分区:
工程技术1区
文献类型:
--
作者:
Lee SA;Yang C

文献摘要

参考文献

被引文献

相似文献

便携式芯片级显微镜设备可以潜在地解决移动的医疗保健和环境监测中的各种成像需求。在这里,我们展示了智能手机相机的适应功能作为一个紧凑的无透镜显微镜。与其他芯片级显微镜方案不同,该方法使用环境照明作为其光源,并且不需要并入专用光源。该方法是基于阴影成像技术,其中样品被放置在图像传感器的表面上,其在照明下捕获直接阴影图像。为了将成像分辨率提高到像素大小之外,我们使用不同照明角度的多个图像执行像素超分辨率重建,这些图像是在用户手动倾斜设备时捕获的,围绕任何环境光源,例如太阳或灯。无透镜成像方案允许在超宽视场(FOV)上进行亚微米分辨率成像。使用定制的android应用程序在设备上执行图像采集和重建,构建用于现场应用的独立成像设备。我们讨论了使用商用智能手机的设备的建设,并展示了我们的系统的成像能力。
Portable chip-scale microscopy devices can potentially address various imaging needs in mobile healthcare and environmental monitoring. Here, we demonstrate the adaptation of a smartphone’s camera to function as a compact lensless microscope. Unlike other chip-scale microscopy schemes, this method uses ambient illumination as its light source and does not require the incorporation of a dedicated light source. The method is based on the shadow imaging technique where the sample is placed on the surface of the image sensor, which captures direct shadow images under illumination. To improve the imaging resolution beyond the pixel size, we perform pixel super-resolution reconstruction with multiple images at different angles of illumination, which are captured while the user is manually tilting the device around any ambient light source, such as the sun or a lamp. The lensless imaging scheme allows for sub-micron resolution imaging over an ultra-wide field-of-view (FOV). Image acquisition and reconstruction is performed on the device using a custom-built android application, constructing a stand-alone imaging device for field applications. We discuss the construction of the device using a commercial smartphone and demonstrate the imaging capabilities of our system.
DOI: 10.1039/c3lc50589h
发表时间: 2013-10-21
期刊: Lab on a chip
影响因子: 6.1
作者:
Navruz I;Coskun AF;Wong J;Mohammad S;Tseng D;Nagi R;Phillips S;Ozcan A
通讯作者: Ozcan A
DOI: 10.1371/journal.pone.0002075
发表时间: 2008-04-30
期刊: PloS one
影响因子: 3.7
作者:
Granot Y;Ivorra A;Rubinsky B
通讯作者: Rubinsky B
DOI: 10.1073/pnas.1110681108
发表时间: 2011-10-11
影响因子: 11.1
作者:
Zheng, Guoan;Lee, Seung Ah;Yang, Changhuei
通讯作者: Yang, Changhuei
DOI: 10.1038/srep01717
发表时间: 2013-04-24
期刊: SCIENTIFIC REPORTS
影响因子: 4.6
作者:
Greenbaum, Alon;Luo, Wei;Khademhosseinieh, Bahar;Su, Ting-Wei;Coskun, Ahmet F.;Ozcan, Aydogan
通讯作者: Ozcan, Aydogan
DOI: 10.1109/jproc.2010.2065210
发表时间: 2010-11-01
影响因子: 20.6
作者:
Ko, JeongGil;Lu, Chenyang;Welsh, Matt
通讯作者: Welsh, Matt