Human cochlear diffusion from the cerebrospinal fluid space with gadolinium contrast.
Human cochlear diffusion from the cerebrospinal fluid space with gadolinium contrast.
复制标题
与钆对比的人耳蜗从脑脊液空间的扩散。
DOI:
10.1016/j.ymthe.2023.08.001
复制
发表时间:
2023
期刊:
影响因子:
--
通讯作者:
Nelson,RickF
中科院分区:
文献类型:
--
作者:
Totten,DouglasJ;Booth,KevinTA;Mosier,KristineM;Cumpston,EvanC;Whitted,Cody;Okechuku,Vanessa;Koontz,NicholasA;Nelson,RickF
Cisternograms are employed clinically to diagnose and localize CSF leaks at the skull base. Spontaneous CSF leaks of the temporal bone occur without an inciting event and are associated with calvarial thinning and bony defects of the skull base through which CSF leaks into the middle ear or mastoid. 1 In challenging diagnostic cases, our team utilizes MRI cisternograms, which involve fluoroscopic lumbar puncture with injection of 500 μL of gadolinium contrast chelate (Gd-BOPTA, MultiHance, Bracco, Milan, Italy) into the intrathecal (CSF) space followed by same-day serial MR imaging performed at 3T field strength. 2 Unexpectedly, we observed rapid and progressive diffusion of gadolinium contrast into the human cochleae and vestibule (Figure 1).We assessed MRI cisternograms from 15 consecutive patients suspected of having a spontaneous CSF leak from 2019 to 2021 (Tables S1 and S2). Eight patients (53%) were found to have a CSF leak on initial or delayed imaging, while seven patients did not. Among the eight patients with a confirmed CSF leak, five were spontaneous, two were traumatic, and one occurred postoperatively following a translabyrinthine resection of a vestibular schwannoma. Gadolinium transduction of the cochlea was observed in 100% of the patients on initial imaging (Figure 1). Vestibular uptake, upon either initial or delayed scan, was observed
登录
查看更多内容
DOI:
--
发表时间:
1989
期刊:
影响因子:
--
作者:
M. Brehélin;L. Drif;L. Baud;N. Boemare
通讯作者:
N. Boemare
影响因子:
3.3
作者:
Pentz,ES;Wright,TR
通讯作者:
Wright,TR
影响因子:
3.3
作者:
Pentz,ES;Black,BC;Wright,TR
通讯作者:
Wright,TR
DOI:
10.1111/j.1600-0749.1988.tb00128.x
发表时间:
1988
期刊:
Pigment cell research
影响因子:
--
作者:
J. R. Jara;F. Solano;J. Lozano
通讯作者:
J. Lozano
影响因子:
2.2
作者:
HAYES, RO
通讯作者:
HAYES, RO