Prevalence of sexually transmitted co-infections in people living with HIV/AIDS: systematic review with implications for using HIV treatments for prevention.
Prevalence of sexually transmitted co-infections in people living with HIV/AIDS: systematic review with implications for using HIV treatments for prevention.
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DOI：
10.1136/sti.2010.047514
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发表时间：
2011-04
影响因子：
3.6
通讯作者：
Turner C
中科院分区：
文献类型：
--
作者：
Kalichman SC;Pellowski J;Turner C
性传播合并感染通过局部炎症过程增加HIV传染性。艾滋病毒/艾滋病感染者中性传播感染的流行对遏制艾滋病毒的普遍传播，特别是对艾滋病毒预防治疗的有效性具有影响。对艾滋病毒/艾滋病感染者性传播感染合并感染研究的系统综述。该审查侧重于感染艾滋病毒后感染的性传播感染。电子数据库和人工搜索找到了增加艾滋病毒传染性的性传播感染的临床和流行病学研究。37项关于性传播感染-艾滋病毒合并感染流行率的研究被定位。对来自发达国家和发展中国家的成年艾滋病毒/艾滋病感染者的研究报告了46个不同样本的性传播感染发生率（33个样本有临床/实验室确认的性传播感染）。确诊性传播感染的总体平均点患病率为16.3% (SD = 16.4)，艾滋病毒/艾滋病感染者的性传播感染患病率中位数为12.4%。最常见的性传播感染是梅毒，患病率中位数为9.5%，淋病为9.5%，衣原体为5%，滴虫病为18.8%。在艾滋病毒诊断时，性传播感染率最高，反映了性传播感染在艾滋病毒传播中的作用。接受艾滋病毒治疗的人与未接受治疗的人之间的性传播感染流行率没有明显差异。性传播感染在艾滋病毒感染者中的流行表明，性传播感染合并感染可能会通过增加生殖器分泌物传染性来破坏使用艾滋病毒治疗进行预防的努力。
Sexually transmitted co-infections increase HIV infectiousness through local inflammatory processes. The prevalence of STI among people living with HIV/AIDS has implications for containing the spread of HIV in general and the effectiveness of HIV treatments for prevention in particular. A systematic review of studies examining STI co-infections in people living with HIV/AIDS. The review focuses on STI contracted after becoming HIV infected. Electronic database and manual searches located clinical and epidemiological studies of STI that increase HIV infectiousness. Thirty seven studies of STI-HIV co-infection prevalence were located. Studies of adults living with HIV/AIDS from developed and developing countries reported STI rates for 46 different samples (33 samples had clinical/laboratory confirmed STI). The overall mean point-prevalence for confirmed STI was16.3% (SD = 16.4), and median 12.4% STI prevalence in people living with HIV/AIDS. The most common STI studied were Syphilis with median 9.5% prevalence, gonorrhea 9.5%, Chlamydia 5%, and Trichamoniasis 18.8% prevalence. STI prevalence was greatest at the time of HIV diagnosis, reflecting the role of STI in HIV transmission. Prevalence of STI among individuals receiving HIV treatment was not appreciably different from untreated persons. The prevalence of STI in people infected with HIV suggests that STI co-infections could undermine efforts to use HIV treatments for prevention by increasing genital secretion infectiousness.
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影响因子：
1.4
作者：
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通讯作者：
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